Results 61 to 70 of about 12,344 (246)

Aerial Geoarchaeological Survey in the Valleys of the Mureş and Arieş Rivers (2009-2013)

Dissertationes Archaeologicae: Ex Instituto Archaeologico Universitatis de Rolando Eötvös Nominatae, 2015
The paper presents the most important results of the Romanian–Hungarian aerial archaeological project, i.e.the intensive topographic research of the Middle Mureş Valley.
Zoltán Czajlik, Sándor Berecki, László Rupnik   +2 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Optimising Deep Learning-Based Segmentation of Crop and Soil Marks with Spectral Enhancements on Sentinel-2 Data

Remote Sensing
This study presents the first systematic investigation into the influence of spectral enhancement techniques on the segmentation accuracy of specific soil and vegetation marks associated with palaeochannels.
Andaleeb Yaseen, Giulio Poggi, Sebastiano Vascon, Arianna Traviglia   +3 more
doaj   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Economic and biological evaluation hybrids of Prunus cerasifera Ehrem. var. pissardii Bail. in conditions of the Southern Urals

BIO Web of Conferences, 2020
Given is the analysis of the basic economic and useful features of 9 genotypes F2 by hybrids of russian cherry plum (Prunus cerasifera var. pissardii) in the conditions of the forest-steppe of the southern Urals.
Slepneva Tatyana, Makarenko Sergey
doaj   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Deep learning-enhanced remote sensing-integrated crop modeling for rice yield prediction

Ecological Informatics
This study introduces a novel crop modeling approach based on cutting-edge computational tools to advance crop production monitoring methodologies, and, thereby, tackle global food security issues.
Seungtaek Jeong, Jonghan Ko, Jong-oh Ban, Taehwan Shin, Jong-min Yeom   +4 more
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Molecular marking and genetic certification: application in plant breeding, biotechnology and identification of horticultural crops

Horticulture and viticulture, 2019
The analysis of contemporary research on molecular marking and genetic certification for use in breeding, biotechnology and identification of horticultural crops is carried out. In Russia and abroad, active work is underway on the identification and certification of garden crops: apple, pear, various types of stone fruit crops, raspberry, strawberry ...
A. A. Yankovskaya, I. V. Knyazeva, M. T. Upadishev   +2 more
openaire   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source