Results 111 to 120 of about 2,200,665 (307)

Bridging the gap: a genetically validated avian chorioallantoic membrane platform for investigation of spontaneous circulating tumor cells

open access: yesMolecular Oncology, EarlyView.
We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth   +17 more
wiley   +1 more source

Crop Yield Skewness and the Normal Distribution [PDF]

open access: yes, 2009
Empirical studies point to negative crop yield skewness, but the literature provides few clear insights as to why. This paper formalizes three points on the matter. Statistical laws on aggregates do not imply a normal distribution.
Hennessy, David
core  

Crop production during the first course of an organic crop rotation trial in Denmark [PDF]

open access: yes, 2000
Three factors are included in a factorial field experiment: 1) fraction of grass-clover and pulses in the rotation (crop rotation), 2) catch crop (with or without catch crop), and 3) manure (with or without animal manure). Manure is applied as slurry in
Olesen, Jørgen E.   +2 more
core   +1 more source

Enhancing Sustainable Agriculture in China: A Meta-Analysis of the Impact of Straw and Manure on Crop Yield and Soil Fertility

open access: yesAgriculture
As the main organic materials, straw and manure play a critical role in soil organic carbon (SOC) sequestration and crop yield in China. This meta-analysis evaluated the impact of straw and manure amendments, both individually and combined, on crop yield,
Zhe Zhao   +6 more
doaj   +1 more source

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

open access: yesMolecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu   +9 more
wiley   +1 more source

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim   +17 more
wiley   +1 more source

Is Area Yield Insurance Competitive with Farm Yield Insurance? [PDF]

open access: yes
This article compares risk reduction from MPCI and GRP crop insurance contracts. The analysis extends and improves on the existing area-yield insurance literature in four important respects.
Skees, Jerry R.   +3 more
core  

Direct and indirect effect of increase of yield: which is bigger?

open access: yesAgricultural and Resource Economics, 2016
The purpose of the article – to provide methodological instruments for calculating direct and indirect economic effects of an increase in the yield of agricultural crops.
Dmytro Parmakli
doaj  

Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer

open access: yesMolecular Oncology, EarlyView.
Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba   +5 more
wiley   +1 more source

An Empirically-Grounded Comparison of the Johnson System versus the Beta as Crop Yield Distribution Models [PDF]

open access: yes
Previous research established that the expanded Johnson system can accommodate any theoretically possible mean-variance-skewness-kurtosis combination.
Ramirez, Octavio A., McDonald, Tanya U.
core  

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