Results 41 to 50 of about 3,063,201 (300)
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
FEBS Letters, EarlyView.Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
Cross-border acquisitions [PDF]
, 2008 Chapter Objectives: - Highlights the motivations for cross-border acquisitions - Provides an overview of trends in cross-border acquisitions - Highlights the empirical evidence on cross-border acquisitions - Highlights the issues in cross-border ...
Vishwanath, S. R. +1 more
core
Enhancing cross-border disaster management in the Balkans: a framework for collaboration part I
Journal of Innovation and EntrepreneurshipThis abstract presents the methodological approach employed in a comprehensive study focusing on decision making in a collaborative manner in disaster management, with a specific emphasis on cross-border disasters in the Balkan region.
Despoina Kanteler, Ioannis Bakouros
doaj +1 more source
FoodsPlate food waste (PFW) in early childhood education is a critical yet understudied issue in Eastern Europe, with implications for nutrition, sustainability, and food security.
Dimitrie Stoica +6 more
doaj +1 more source
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
Cross Border Tourism and Regional Development: Case Indonesia-Timor Leste Cross Border
Ekuilibrium: Jurnal Ilmiah Bidan Ilmu Ekonomi, 2020 This study aims to: (i) describe the perception of stakeholder about cross border tourism in Wini Indonesia and the Oecusse-timor Leste, (ii) analyze the impact of cross border tourism on the regional development.
Werenfridus Taena, Felisisima Afoan
doaj +1 more source
Relationship between Cyber Security and Civil Protection in the Greek Reality
Applied Sciences, 2023 The links between cybersecurity and civil protection in the last decades became strong due to the rapid increase in the use of Informatics Technologies (IT) worldwide and the need to increase citizens’ protection from various disasters and uncertainties.
Stavros Kalogiannidis +3 more
doaj +1 more source
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
FEBS Letters, EarlyView.This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
Hump-Shaped Cross-Price Effects and the Extensive Margin in Cross-Border Shopping
, 2022 This paper examines the effect of cross-border shopping on grocery demand in Norway using monthly store x category sales data from Norway's largest grocery chain 2012-2016.
Ulsaker, Simen A., +2 more
core +1 more source