Results 51 to 60 of about 480,425 (296)
Cross Border Tourism and Regional Development: Case Indonesia-Timor Leste Cross Border
This study aims to: (i) describe the perception of stakeholder about cross border tourism in Wini Indonesia and the Oecusse-timor Leste, (ii) analyze the impact of cross border tourism on the regional development.
Werenfridus Taena, Felisisima Afoan
doaj +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Uncertainty Measurement for Fuzzy Set-Valued Data
Uncertainty measurement (UM) can offer new visual angle for data analysis. A fuzzy set-valued information system (FSVIS) indicates an information system (IS) where its information values are fuzzy sets.
Sichun Wang, Yini Wang, Hongxiang Tang
doaj +1 more source
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
AAA+ protein unfoldases—the Moirai of the proteome
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley +1 more source
Global demand for sustainable food packaging materials has intensified research on bio-based biopolymer systems capable of delivering functional compounds.
Dimitrie Stoica +4 more
doaj +1 more source
Cross-Border Mergers and Cross-Border Takeovers Compared
The EU rules on cross-border mergers provide a legal framework for the aggregation of firms across the borders of EU Member States (Directive (EU) 2017/1132). These rules are not alone in pursuing this aim, as the takeover bid directive (Directive 2004/25/EC) also contributes to fostering cross-border combinations of European firms.
openaire +4 more sources
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
In this paper, the maximum principle of variable-order fractional diffusion equations and the estimates of fractional derivatives with higher variable order are investigated.
Guangming Xue +5 more
doaj +1 more source
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source

