Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Global demand for sustainable food packaging materials has intensified research on bio-based biopolymer systems capable of delivering functional compounds.
Dimitrie Stoica +4 more
doaj +1 more source
Uncertainty Measurement for Fuzzy Set-Valued Data
Uncertainty measurement (UM) can offer new visual angle for data analysis. A fuzzy set-valued information system (FSVIS) indicates an information system (IS) where its information values are fuzzy sets.
Sichun Wang, Yini Wang, Hongxiang Tang
doaj +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Cross-border and local cooperation on the island of Ireland : an economic perspective [PDF]
Revised version of a paper presented at a study group meting in Newry, 13 September 2005, as part of the programme Mapping frontiers, plotting pathways: routes to North-South cooperation in a divided island.Cross-border and local cooperation can foster
Roper, Stephen
core +1 more source
Quality requirements for cross-border care in Europe: a qualitative study of patients', professionals' and healthcare financiers' views. [PDF]
BACKGROUND: In the past decade the issue of patient mobility has emerged on the European health policy agenda. Although the volume of patients crossing borders to obtain healthcare is low, it is increasing continuously and, due to its legal, financial ...
Vallejo, P +13 more
core +1 more source
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
Land-border crossings between Canada and the United States facilitate the movement of approximately 59 % of the goods traded between the two countries. Consequently, these border facilities experience heavy truck traffic daily.
Hanna Maoh, Sidra Anis
doaj +1 more source
The socio-economic impacts of Singaporean cross-border tourism in Malaysia and Indonesia [PDF]
Cross-border tourism is often proposed by governments as an incentive for economic growth, but critics have suggested that its impacts are, in fact, overplayed. This paper presents research in the Indonesia-Malaysia-Singapore Growth Triangle.
Hampton, Mark P.
core
‘What are you going to do, confiscate their passports?’ Professional perspectives on cross-border reproductive travel [PDF]
Objective: This article reports findings from a UK-based study which explored the phenomenon of overseas travel for fertility treatment. The first phase of this project aimed to explore how infertility clinicians and others professionally involved in ...
Pacey, Allan +10 more
core +1 more source

