Results 71 to 80 of about 3,063,201 (300)
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
A cross-border approach to mental health promotion.
, 2012 This paper reports on preliminary findings from a project commissioned by the Centre for Cross Border Studies, Armagh. The project is concerned with cross border co-operation in the development of mental health promotion in the North and South of Ireland,
Barry, Margaret M., Friel, Sharon
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Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Cross-Border Cooperation: Subverting Sovereignty?
, 2018 Work on European spatial planning has led me to criticise what I call territorialism.It conceives of the world in terms of a seamless cover of sovereign stateslooking after its territory each as if it were its property.
Faludi, A.K.F. (author)
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Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
Sustaining cross-border cooperation : a cross-sectoral case study approach
, 2006 Revised version of a paper presented at the final conference of the Mapping frontiers, plotting pathways: routes to North-South cooperation in a divided island programme, City Hotel, Armagh, 19-20 January 2006This paper is based on a set of case studies ...
O'Dowd, Liam +2 more
core
Trends and regional patterns of cross-border mergers and acquisitions: A case of Malaysian and Indonesian acquirers [PDF]
, 2012 Progress of cross-border mergers and acquisitions (M&A) in Asian region demonstrates an upstream pattern although the economy in Europe is unhealthy.In fact, many cross-border deals in Europe are dominated by Asian and US acquirers.In 2010, Asia Pacific
Jedin, Mohd. Haniff
core
DigitalGeographyLab/functional-cross-border-regions-nordics: v1.0
, 2022 This repo contains code used in the article "The effect of COVID-19 on cross-border mobilities of people and functional border regions: the Nordic case study from Twitter data"
Olle Järv, Håvard Wallin Aagesen
core +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source