Results 101 to 110 of about 1,547,985 (301)
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Source separation and localisation via tensor decomposition for distributed arrays
The Journal of Engineering, 2019 This study focuses on the problem of power spectra separation and localisation of multiple sources using distributed arrays. First, the array structure and signal model are discussed. By cross-correlating the multi-channel received signals in time-domain,
Yuanbing Cheng, Yapeng He
doaj +1 more source
Statistical Anisotropies in Gravitational Waves in Solid Inflation
, 2014 Solid inflation can support a long period of anisotropic inflation. We calculate the statistical anisotropies in the scalar and tensor power spectra and their cross-correlation in anisotropic solid inflation.
Akhshik, Mohammad +3 more
core +2 more sources
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
S-193 impulse response cross correlation [PDF]
The author has identified the following significant results. A significant result was the realization that the phase information, normally lost in envelope detection and sampling, could have been preserved if the samples were taken at the peaks of the ...
Hayre, H. S.
core +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
THE EFFICIENCY OF SELECTIVE TIDAL STREAM TRANSPORT IN GLASS EEL ENTERING THE GIRONDE (FRANCE)
Knowledge and Management of Aquatic Ecosystems, 2005 Traditional estimation of migration speed is based on telemetry or marking of individual fish. Only a few numbers of fishes (or batches) are followed, often over short periods of time.
BEAULATON L., CASTELNAUD G.
doaj +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source