Results 81 to 90 of about 1,413,737 (264)
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Frontiers in Network PhysiologyEarly warnings signs (EWSs) can anticipate abrupt changes in system state, known as “critical transitions,” by detecting dynamic variations, including increases in variance, autocorrelation (AC), and cross-correlation.
Véronique Legault +4 more
doaj +1 more source
Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
On the Cross-Correlation of Golomb Costas Permutations
IEEE Transactions on Information TheoryIn the most interesting case of safe prime powers $q$, Gómez and Winterhof showed that a subfamily of the family of Golomb Costas permutations of $\{1,2,\ldots,q-2\}$ of size $φ(q-1)$ has maximal cross-correlation of order of magnitude at most $q^{1/2}$.
Huaning Liu, Arne Winterhof
openaire +2 more sources
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Mechanisms for similarity matching in disparity measurement
Frontiers in Psychology, 2014 Early neural mechanisms for the measurement of binocular disparity appear to operate in a manner consistent with cross-correlation-like processes. Consequently, cross-correlation, or cross-correlation-like procedures have been used in a range of models ...
Ross eGoutcher, Paul B Hibbard
doaj +1 more source
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
A semi-automatic approach to identify first arrival time: the Cross-Correlation Technique
Earth Sciences Research Journal, 2014 The high-quality interpretation of seismic refraction data depends on the accurate and reliable identification of the first arrival times. First arrivals can be identified on a graphic or image by conventional picking, but this process depends on ...
Mustafa Senkaya, Hakan Karslı
doaj +1 more source
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source