Results 111 to 120 of about 9,414,622 (284)

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

open access: yesFEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf   +6 more
wiley   +1 more source

Baryon acoustic oscillations with the cross-correlation of spectroscopic and photometric samples

open access: yes, 2013
The baryon acoustic oscillation (BAO) experiment requires a sufficiently dense sampling of large-scale structure tracers with spectroscopic redshift, which is observationally expensive especially at high redshifts $z\simgt 1$.
Nishizawa, Atsushi J.   +2 more
core   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Multifractal detrended cross-correlation analysis for two nonstationary signals

open access: yes, 2008
It is ubiquitous in natural and social sciences that two variables, recorded temporally or spatially in a complex system, are cross-correlated and possess multifractal features.
A. N. Kravchenko   +3 more
core   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

THE EFFICIENCY OF SELECTIVE TIDAL STREAM TRANSPORT IN GLASS EEL ENTERING THE GIRONDE (FRANCE)

open access: yesKnowledge and Management of Aquatic Ecosystems, 2005
Traditional estimation of migration speed is based on telemetry or marking of individual fish. Only a few numbers of fishes (or batches) are followed, often over short periods of time.
BEAULATON L., CASTELNAUD G.
doaj   +1 more source

Observational Constraints on Kinetic Gravity Braiding from the Integrated Sachs-Wolfe Effect

open access: yes, 2012
The cross-correlation between the integrated Sachs-Wolfe (ISW) effect and the large scale structure (LSS) is a powerful tool to constrain dark energy and alternative theories of gravity.
Kazuhiro Yamamoto   +3 more
core   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

open access: yesMolecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan   +9 more
wiley   +1 more source

Application of early warning signs to physiological contexts: a comparison of multivariate indices in patients on long-term hemodialysis

open access: yesFrontiers in Network Physiology
Early warnings signs (EWSs) can anticipate abrupt changes in system state, known as “critical transitions,” by detecting dynamic variations, including increases in variance, autocorrelation (AC), and cross-correlation.
Véronique Legault   +4 more
doaj   +1 more source

On the typical values of the cross-correlation measure

open access: yes, 2016
Gyarmati, Mauduit and S\'ark\"ozy introduced the \textit{cross-correlation measure} $\Phi_k(\mathcal{F})$ to measure the randomness of families of binary sequences $\mathcal{F} \subset \{-1,1\}^N$.
Mérai, László
core   +1 more source

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