Results 91 to 100 of about 4,913,448 (308)
Wally and the Major [picture] : at cross purposes /
, 1967 Part of the Stan Cross Archive of cartoons and drawings, 1912-1974.; Inscription: "Stan Cross 7/87"--In ink, lower right. "8335 Thur Apr 13 At Cross Purposes"--In ink, right margin; "8335"--In pencil, upper right corner.; Also available in an electronic ...
Cross, Stan, 1888-1977.
core
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Remarkable effect of alkynyl substituents on the fluorescence properties of a BN-phenanthrene
Beilstein Journal of Organic Chemistry, 2019 A series of BN-phenanthrenes with substituents of a diverse nature have been synthesized by palladium-catalyzed cross-coupling reactions of a common chloro-substituted precursor, which was made from readily available materials in only four steps ...
Alberto Abengózar +3 more
doaj +1 more source
New Advances in Titanium-Mediated Free Radical Reactions
Molecules, 2012 Titanium complexes have been widely used as catalysts for C‑C bond-forming processes via free-radical routes. Herein we provide an overview of some of the most significant contributions in the field, that covers the last decade, emphasizing the
Angelo Clerici +4 more
doaj +1 more source
Wally and the Major [picture] : at cross purposes /
, 1969 Part of the Stan Cross Archive of cartoons and drawings, 1912-1974.; Inscription: "Stan Cross 9/80"--In ink, lower right. "8953 Tue Apr 8. At Cross Purposes"--In ink, right margin; "8953"--In pencil, upper right corner.; Also available in an electronic ...
Cross, Stan, 1888-1977.
core
Molecular Oncology, EarlyView.Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source
Photochemical Carbosulfonylative Cross-Coupling of Alkenes
Organic & Biomolecular ChemistryAn alkylative carbosulfonylation protocol for the formation of C-S and C-C bonds between sulfinate salts and readily available alkenes under visible light irradiation is reported. This approach formally couples two alkene molecules to give access to highly functionalized sp3 sulfone products following two sequential radical additions. Homocoupled
Vanessa E. Becker +2 more
openaire +2 more sources
Synthesis of the heterocyclic core of the D-series GE2270
Beilstein Journal of Organic Chemistry, 2017 A straightforward enantiomerically pure synthesis of the heterocyclic core of the D-series GE2270 is reported. The synthetic strategy combines the Hantzsch thiazole’s building condensation with a cross-coupling reaction including direct C–H hetarylation ...
Christophe Berini +5 more
doaj +1 more source
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
Beilstein Journal of Organic Chemistry, 2016 Pd-catalysed C–C bond formation is an essential tool within the pharmaceutical and agrochemical industries. Many of these reactions rely heavily on polar aprotic solvents; however, despite their utility, these solvents are incompatible with the drive ...
Kirsty L. Wilson +5 more
doaj +1 more source