Results 91 to 100 of about 3,560,207 (306)
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source
Wally and the Major [picture] : at cross purposes /
Part of the Stan Cross Archive of cartoons and drawings, 1912-1974.; Inscription: "Stan Cross 7/87"--In ink, lower right. "8335 Thur Apr 13 At Cross Purposes"--In ink, right margin; "8335"--In pencil, upper right corner.; Also available in an electronic ...
Cross, Stan, 1888-1977.
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Remarkable effect of alkynyl substituents on the fluorescence properties of a BN-phenanthrene
A series of BN-phenanthrenes with substituents of a diverse nature have been synthesized by palladium-catalyzed cross-coupling reactions of a common chloro-substituted precursor, which was made from readily available materials in only four steps ...
Alberto Abengózar +3 more
doaj +1 more source
New Advances in Titanium-Mediated Free Radical Reactions
Titanium complexes have been widely used as catalysts for C‑C bond-forming processes via free-radical routes. Herein we provide an overview of some of the most significant contributions in the field, that covers the last decade, emphasizing the
Angelo Clerici +4 more
doaj +1 more source
Photochemical Carbosulfonylative Cross-Coupling of Alkenes
Polarity mismatched carbosulfonylative cross-coupling of alkenes gives highly functionalized sp 3 sulfone products using an Ir photocatalyst and 456 nm blue LEDs.
Vanessa E. Becker +2 more
openaire +2 more sources
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
Wally and the Major [picture] : at cross purposes /
Part of the Stan Cross Archive of cartoons and drawings, 1912-1974.; Inscription: "Stan Cross 9/80"--In ink, lower right. "8953 Tue Apr 8. At Cross Purposes"--In ink, right margin; "8953"--In pencil, upper right corner.; Also available in an electronic ...
Cross, Stan, 1888-1977.
core
Synthesis of the heterocyclic core of the D-series GE2270
A straightforward enantiomerically pure synthesis of the heterocyclic core of the D-series GE2270 is reported. The synthetic strategy combines the Hantzsch thiazole’s building condensation with a cross-coupling reaction including direct C–H hetarylation ...
Christophe Berini +5 more
doaj +1 more source
Screening and epitope characterization of Nidogen‐2‐specific nanobodies
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen +9 more
wiley +1 more source
Jessie Cross on park bench, ca. 1924 [picture] /
Part of the Stan Cross Archive of cartoons and drawings, 1912-1974.; Inscription: "Jessie Cross taken 1915"--In ink on verso.; Title devised by cataloguer.; Also available in an electronic version via the internet at: http://nla.gov.au/nla.pic ...
Cross, Stan, 1888-1977.
core

