Results 71 to 80 of about 3,560,207 (306)
Functionalization of heterocyclic compounds using polyfunctional magnesium and zinc reagents
Beilstein Journal of Organic Chemistry, 2011 In this review we summarize the most important procedures for the preparation of functionalized organzinc and organomagnesium reagents. In addition, new methods for the preparation of polyfunctional aryl- and heteroaryl zinc- and magnesium compounds, as ...
Paul Knochel +7 more
doaj +1 more source
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
Wally and the Major [picture] : cross purposes /
, 1958 Part of the Stan Cross Archive of cartoons and drawings, 1912-1974.; Inscription: "Stan Cross 8/47"--Lower right. "5496 Mon Mar 10 Cross Purposes"--In ink, right margin; "5419"--In ink, upper right corner; "11"--In pencil, upper left corner.; Also ...
Cross, Stan, 1888-1977.
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A Systematic Investigation into Bisphosphine Ligands for Nickel-Catalyzed C(sp2)–N Cross-Coupling
, 2023 Research into transition metal-catalyzed C–N cross-coupling reactions has been driven by a need for robust and facile synthetic routes towards bioactive molecules which are rich in C–N linkages. The use of Pd-based catalysts in Buchwald-Hartwig Amination
Martinek, Nicole
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Beilstein Journal of Organic Chemistry, 2019 A methodology for the solid-phase synthesis of biaryl bicyclic peptides containing a Phe-Phe, a Phe-Tyr or a Tyr-Tyr motif has been devised. This approach comprises two key steps.
Iteng Ng-Choi +3 more
doaj +1 more source
3,4′,5,5′-Tetramethoxy-2′-methylbiphenyl-4-ol
IUCrData, 2019 The asymmetric unit of the title compound, C17H20O5, contains two independent molecules, A and B, with similar geometries [dihedral angles between the phenyl rings = 56.19 (8) and 54.98 (7)°, respectively].
Barbara Gleede +3 more
doaj +1 more source
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
Wally and the Major [picture] : cross purposes /
, 1968 Part of the Stan Cross Archive of cartoons and drawings, 1912-1974.; Inscription: "Stan Cross 8/195"--In ink, lower right. "8757 Fri Aug 16 Cross Purposes"--In ink, right margin; "8757"--In pencil, upper right corner; "6"--In pencil, upper left corner ...
Cross, Stan, 1888-1977.
core
Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
Compensation of Cross-Coupling in MIMO Inductive Power Transfer Systems
IEEE AccessThis paper proposes a design principle for reactance compensation circuit for multiple-input multiple-output (MIMO) inductive power transfer (IPT) where the primary side employs a coil array to send power to a receiving coil array located at the ...
Quoc-Trinh Vo +3 more
doaj +1 more source