Results 71 to 80 of about 4,913,448 (308)
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Functionalization of heterocyclic compounds using polyfunctional magnesium and zinc reagents
Beilstein Journal of Organic Chemistry, 2011 In this review we summarize the most important procedures for the preparation of functionalized organzinc and organomagnesium reagents. In addition, new methods for the preparation of polyfunctional aryl- and heteroaryl zinc- and magnesium compounds, as ...
Paul Knochel +7 more
doaj +1 more source
Wally and the Major [picture] : cross purposes /
, 1970 Part of the Stan Cross Archive of cartoons and drawings, 1912-1974.; Inscription: "Stan Cross 70/24"--In ink, lower right. "9205 Wed Jan 28. Cross Purposes"--In ink, right margin; "9205"--In pencil, upper right corner.; Also available in an electronic ...
Cross, Stan, 1888-1977.
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A Systematic Investigation into Bisphosphine Ligands for Nickel-Catalyzed C(sp2)–N Cross-Coupling
, 2023 Research into transition metal-catalyzed C–N cross-coupling reactions has been driven by a need for robust and facile synthetic routes towards bioactive molecules which are rich in C–N linkages. The use of Pd-based catalysts in Buchwald-Hartwig Amination
Martinek, Nicole
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Translophagy—A potential link between autophagy impairment and translational errors
FEBS Letters, EarlyView.Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
Beilstein Journal of Organic Chemistry, 2019 A methodology for the solid-phase synthesis of biaryl bicyclic peptides containing a Phe-Phe, a Phe-Tyr or a Tyr-Tyr motif has been devised. This approach comprises two key steps.
Iteng Ng-Choi +3 more
doaj +1 more source
3,4′,5,5′-Tetramethoxy-2′-methylbiphenyl-4-ol
IUCrData, 2019 The asymmetric unit of the title compound, C17H20O5, contains two independent molecules, A and B, with similar geometries [dihedral angles between the phenyl rings = 56.19 (8) and 54.98 (7)°, respectively].
Barbara Gleede +3 more
doaj +1 more source
Wally and the Major [picture] : cross purposes /
, 1968 Part of the Stan Cross Archive of cartoons and drawings, 1912-1974.; Inscription: "Stan Cross 8/195"--In ink, lower right. "8757 Fri Aug 16 Cross Purposes"--In ink, right margin; "8757"--In pencil, upper right corner; "6"--In pencil, upper left corner ...
Cross, Stan, 1888-1977.
core
Prospecting the protein design landscape
FEBS Letters, EarlyView.This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona +4 more
wiley +1 more source
Artificial molecular machines and motors—Design and control of nanoscale motion
FEBS Letters, EarlyView.Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley +1 more source