Results 61 to 70 of about 3,560,207 (306)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Cross family christmas card, 1954 [picture] : "merry xmas and a happy new year to from stan cross and his family december 1954" /

open access: yes, 1954
Part of the Stan Cross Archive of cartoons and drawings, 1912-1974.; Copy of original drawing. "Merry Xmas and a Happy New Year From Stan Cross and his Family December 1954"; Also available in an electronic version via the internet at: http://nla.gov.au ...
Cross, Stan, 1888-1977.
core   +2 more sources

N-Arylation of amines, amides, imides and sulfonamides with arylboroxines catalyzed by simple copper salt/EtOH system

open access: yesBeilstein Journal of Organic Chemistry, 2008
The coupling of arylboroxines with a variety of amines, amides, imides and sulfonamides catalyzed by a copper salt/EtOH system has been developed. In the absence of a base or additive the corresponding N-arylation products were obtained in moderate to ...
Zhang-Guo Zheng   +4 more
doaj   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

open access: yesMolecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel   +6 more
wiley   +1 more source

Copper-catalyzed arylation of alkyl halides with arylaluminum reagents

open access: yesBeilstein Journal of Organic Chemistry, 2015
We report a Cu-catalyzed coupling between triarylaluminum reagents and alkyl halides to form arylalkanes. The reaction proceeds in the presence of N,N,N’,N’-tetramethyl-o-phenylenediamine (NN-1) as a ligand in combination with CuI as a catalyst.
Bijay Shrestha, Ramesh Giri
doaj   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Ni-Catalyzed Electrochemical C(sp2)−C(sp3) Cross-Coupling Reactions

open access: yes, 2020
Nickel (Ni) catalyzed carbon-carbon (C−C) cross-coupling has been considerably developed in last decades and has demonstrated unique reactivities compared to palladium.
maowei, hu   +4 more
core   +1 more source

Double N-arylation reaction of polyhalogenated 4,4’-bipyridines. Expedious synthesis of functionalized 2,7-diazacarbazoles

open access: yesBeilstein Journal of Organic Chemistry, 2012
Unusual 2,7-diazacarbazoles were prepared in one step from readily available tetra-halogenated 4,4’-bipyridines by using a double N-arylation reaction in the presence of the Pd–XPhos catalyst system.
Mohamed Abboud   +2 more
doaj   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Wally and the Major [picture] : cross purposes /

open access: yes, 1969
Part of the Stan Cross Archive of cartoons and drawings, 1912-1974.; Inscription: "Stan Cross 9/66"--In ink, lower right. "8939 Tue Mar 18 Cross Purposes"--In ink, right margin; "8939"--In pencil, upper right corner.; Also available in an electronic ...
Cross, Stan, 1888-1977.
core  

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