Results 61 to 70 of about 978,045 (338)

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

Curiosity and its role in cross-cultural knowledge creation [PDF]

open access: yes, 2016
This paper explores the role of curiosity in promoting cross-cultural knowledge creation and competence development. It is based on a study with four international higher educational institutions, all of which offer management and business education ...
Mikhaylov, Natalie S.
core   +1 more source

Mechanisms of parasite‐mediated disruption of brain vessels

open access: yesFEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira   +3 more
wiley   +1 more source

Developing Cross-Cultural Relationships [PDF]

open access: yes, 2005
Linfield College students left more than a newly constructed softball field and a freshly painted mural in Mexico last spring.
Davis, Laura
core   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

A Primer to (Cross-Cultural) Multi-Group Invariance Testing Possibilities in R

open access: yesFrontiers in Psychology, 2019
Psychology has become less WEIRD in recent years, marking progress toward becoming a truly global psychology. However, this increase in cultural diversity is not matched by greater attention to cultural biases in research.
Ronald Fischer   +2 more
doaj   +1 more source

Evaluation in media texts: a cross-cultural linguistic investigation [PDF]

open access: yes, 2004
A quantitative/interpretative approach to the comparative linguistic analysis of media texts is proposed and applied to a contrastive analysis of texts from the English-language China Daily and the UK Times to look for evidence of differences in what ...
Chen, L.
core   +1 more source

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

open access: yesFEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf   +6 more
wiley   +1 more source

Cross-Cultural Meta-Analyses

open access: yesOnline Readings in Psychology and Culture, 2003
Introduction The impact of culture on psychological functioning has received increasing attention over the past decades. Scrutiny of the PsycInfo database (May 2006) shows that the percentage of studies addressing culture, ethnicity, or race has been steadily increasing from 4.6% of all published psychological studies between 1960 and 1970 to 9.3 ...
openaire   +5 more sources

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

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