Results 81 to 90 of about 7,877,791 (334)

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

A Primer to (Cross-Cultural) Multi-Group Invariance Testing Possibilities in R

open access: yesFrontiers in Psychology, 2019
Psychology has become less WEIRD in recent years, marking progress toward becoming a truly global psychology. However, this increase in cultural diversity is not matched by greater attention to cultural biases in research.
Ronald Fischer   +2 more
doaj   +1 more source

PUBLIC PHILOSOPHY: CROSS-CULTURAL AND MULTI-DISCIPLINARY [PDF]

open access: yes, 2015
In this paper I propose a future direction for comparative philosophy on which it enters the space of public philosophy by capitalizing on the fact that it is already cross-cultural, and adding multi-disciplinary research to its proper foundation.
VAIDYA, ANAND JAYPRAKASH
core   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

open access: yesMolecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero   +11 more
wiley   +1 more source

Cross-Cultural Meta-Analyses

open access: yesOnline Readings in Psychology and Culture, 2003
Introduction The impact of culture on psychological functioning has received increasing attention over the past decades. Scrutiny of the PsycInfo database (May 2006) shows that the percentage of studies addressing culture, ethnicity, or race has been steadily increasing from 4.6% of all published psychological studies between 1960 and 1970 to 9.3 ...
openaire   +5 more sources

Curiosity and its role in cross-cultural knowledge creation [PDF]

open access: yes, 2016
This paper explores the role of curiosity in promoting cross-cultural knowledge creation and competence development. It is based on a study with four international higher educational institutions, all of which offer management and business education ...
Mikhaylov, Natalie S.
core   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

Convergencia y divergencia en el comportamiento de los consumidores

open access: yesCommunication & Society (Formerly Comunicación y Sociedad), 2002
Uno de los aspectos de la globalización es la convergencia de las rentas, de los medios y de la tecnología de los países. Muchos autores esperan que esta convergencia lleve a un comportamiento homogéneo entre los consumidores.
Marieke de-Mooij
doaj  

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Is Susila Budhi Dharma (Subud) a Religion?

open access: yesAl-Albab, 2017
The government of Indonesia has recognized six offical religions based on certain categories by law. Susila Budhi Dharma known as SUBUD is not included as one of them.
Watini Watini
doaj   +1 more source

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