Results 71 to 80 of about 5,925,554 (260)
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
Uncertainty aware domain incremental learning for cross domain depression detection
Deep learning techniques have demonstrated significant promise for detecting Major Depressive Disorder (MDD) from textual data but they still face limitations in real-world scenarios.
Zita Lifelo +3 more
doaj +1 more source
STOD: Towards Scalable Task-Oriented Dialogue System on MultiWOZ-API
Task-oriented dialogue systems (TODs) enable users to complete specific goals and are widely used in practice. Although existing models have achieved delightful performance for single-domain dialogues, scalability to new domains is far from well explored.
Hengtong Lu, Caixia Yuan, Xiaojie Wang
doaj +1 more source
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
Prospecting the protein design landscape
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona +4 more
wiley +1 more source
Cross-Domain Concept formation using HR
Many interesting and valuable concepts in mathematics are essentially `cross-domain' in nature, i.e. they relate objects, ideas and theories from more than one area of mathematics.
Graham Steel +1 more
core
RNA‐related functions of BRCA2 in transcription, replication, and genome stability
Beyond its role in homologous recombination, BRCA2 regulates R‐loop homeostasis, DNA–RNA hybrid resolution, RNA polymerase II dynamics, and transcriptional activation. Disruption of any of these functions can contribute to genome instability, inflammatory signaling, and tumorigenesis. BRCA2 is a central tumor suppressor protein best known for its roles
Lucia Alvaro‐Aranda +2 more
wiley +1 more source
Wally and the Major [picture] : cross purposes /
Part of the Stan Cross Archive of cartoons and drawings, 1912-1974.; Inscription: "Stan Cross 9/66"--In ink, lower right. "8939 Tue Mar 18 Cross Purposes"--In ink, right margin; "8939"--In pencil, upper right corner.; Also available in an electronic ...
Cross, Stan, 1888-1977.
core
Part of the Stan Cross Archive of cartoons and drawings, 1912-1974.; Two copies of original drawing. "Merry Xmas and a Happy New Year From Stan Cross and his Family December 1954"; Also available in an electronic version via the internet at: http://nla ...
Cross, Stan, 1888-1977.
core +2 more sources
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise +5 more
wiley +1 more source

