Results 41 to 50 of about 5,964,900 (273)

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source

Smaller is better: nanobodies meet NMR

FEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy

FEBS Letters, EarlyView.
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley   +1 more source

Authentication and Authorization of Users and Services in Dynamic Military SOA Environments

Journal of Telecommunications and Information Technology, 2023
The problem of user authentication and authorization is usually being solved in a single system. Federated environment assumes heterogeneity of systems, which brings the problem of mutual users and services authentication and authorization.
Bartosz Jasiul, Joanna Śliwa, Rafał Piotrowski, Robert Goniacz   +3 more
doaj   +1 more source

Soft motions encoded by the fold and mediated by conserved hinge sites drive V‐ATPase allosteric machinery and autoinhibition

FEBS Letters, EarlyView.
Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana, Xiaowei Bogetti, Stuti Sharma, Ivet Bahar   +3 more
wiley   +1 more source

A Bran-New Cross-Domain Authentication Model Based on Lattice

, 2010
A bran-new lattice based cross-domain model is proposed to solve the shortcomings of the existing authentication model. Firstly, using the lattice theory, this model builds credit-domain alliance and user alliance on the two dimensional coordinates to ...
Feng Man Miao, Zhan Ting Yuan, Qiu Yu Zhang   +2 more
core   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Cross domain authentication with open ID for web-services

, 2011
Cross domain authentication for web services is important when web services in one organization are accessed from another. This paper presents the implementations of cross domain authentication in web service environment with OpenID.
Attenayake, S, Siriwardena, P, Wijekoon, S, Mahagederawatte, H, Dias, G, Wijenayake, D   +5 more
core   +1 more source

Cross-domain Authentication Alliance Protocol Based on Isomorphic Groups

Journal of Computers, 2011
With the development of information technology in distributed network, such as cloud computing and grid computing. They need mutual coordination resources among the various areas to meet the requirement in infinite speed and infinite space of information technology for people.
Qikun Zhang, Jun Zheng 0007, Yu-an Tan 0001, Ruifang Wang, Yuanzhang Li 0001   +4 more
openaire   +1 more source

Enabling Practical IPsec authentication for the Internet [PDF]

, 2006
On the Move to Meaningful Internet Systems 2006: OTM 2006 Workshops (First International Workshop on Information Security (IS'06), OTM Federated Conferences and workshops). Montpellier, Oct,/Nov.
Delgado Kloos, Carlos, Muñoz Organero, Mario, García-Martínez, Alberto, Mario Muñoz Organero, Alberto García-Martínez, Muñoz Merino, Pedro José, Muñoz-Merino, Pedro J., Carlos Delgado Kloos, Muñoz-Organero, Mario, Pedro J. Muñoz Merino   +9 more
core   +1 more source