Results 101 to 110 of about 170,253 (336)
Comparing and contrasting Escherichia coli and Mycobacterium tuberculosis mechanosensitive channels (MscL) - New gain of function mutations in the loop region [PDF]
Sequence analysis of 35 putative MscL homologues was used to develop an optimal alignment for Escherichia coli and Mycobacterium tuberculosis MscL and to place these homologues into sequence subfamilies.
Dougherty, Dennis A.+3 more
core
Polybutadiene Cross-Linked With Various Diols – Effect On Thermal Stability [PDF]
The relationship between cross-linking and thermal stability as related to polybutadiene is the focus of current research. Cross-linked polybutadienes have been prepared using various diols as the cross-linking agent.
McKinney, Michael A.+2 more
core +2 more sources
4,4'-Difluoro-3,3'-dinitrophenylsulfone as a Cross-Linking Reagent for Lysozyme
SummaryActive cross-linked derivatives of egg-white lysozyme have been prepared by reaction with 4,4′-difluoro-3,3′-dinitrophenyl-sulfone and isolated from excess reagents and salts by gel chromatography. Lytic activity of the enzyme at pH 9.21 is almost abolished in one cross-linked derivative which still retains 20% of its lytic activity at pH 6.24 ...
James L. Long, Clarence O. Stevens
openaire +3 more sources
RhoA and Rac1 as Mechanotransduction Mediators in Colorectal Cancer
Analysing RhoA and Rac1 protein levels in Colorectal cancer (CRC) samples under mechanical strain highlights their potential as diagnostic markers. Monitoring their activity could offer valuable insights into how cancer spreads, paving the way for new approaches to better understand and diagnose colorectal cancer.
Sharda Yadav+5 more
wiley +1 more source
Using supramolecular monomers, various hydrogel culture systems were formulated to culture protoplasts; including 2D, 2.5D, and 3D hydrogels. Depending on the culture platform, bioactive functionalization led to protoplast enlargement (2D and 2.5D) or plasmolysis (3D). This work shows the potential to modularly engineer synthetic platforms for cellular
Maritza M. Rovers+3 more
wiley +1 more source
The removal of pharmaceutical contaminants like the anticonvulsant carbamazepine (CBZ) from water sources is a growing environmental challenge. This study explores the development of molecularly imprinted polymers (MIPs) tailored for CBZ adsorption using
Elettra Savigni+5 more
doaj +1 more source
Immunotherapies based on natural killer (NK) cells are among the most promising therapies under development for the treatment of so far incurable forms of leukemia and other types of cancer.
Erhard Hofer, Ulrike Koehl
doaj +1 more source
Proteomic identification of heterogeneous nuclear ribonucleoprotein L as a novel component of SLM/Sam68 nuclear bodies [PDF]
Background: Active pre-mRNA splicing occurs co-transcriptionally, and takes place throughout the nucleoplasm of eukaryotic cells. Splicing decisions are controlled by networks of nuclear RNA-binding proteins and their target sequences, sometimes in ...
Bindereif, A.+10 more
core +7 more sources
LIN28B Promotes Cancer Cell Dissemination and Angiogenesis
Children diagnosed with high‐risk neuroblastoma have a 5‐year event‐free survival rate of less than 50% and poor outcomes after recurrence. Deregulation of the LIN28B oncogene can be addressed in these patients. Upregulation of LIN28B is shown to support the metastatic cascade.
Diana Corallo+8 more
wiley +1 more source
The stabilisation of receptor structure in low cross-linked MIPs by an immobilised template [PDF]
In molecularly imprinted polymers (MIPs) a high level of cross-linking is usually important for preserving the receptor structure. We propose here an alternative approach for stabilising binding sites, which involves the use of an immobilised template.
Chianella, Iva+6 more
core +1 more source