Results 111 to 120 of about 6,986,470 (307)
Journal of Orthopaedic Surgery, 2008 Purpose. To assess the criterion validity, repeatability, and the missing value protocol of the reduced Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) function scale (‘reduced scale’). Methods.
SL Whitehouse, RW Crawford, ID Learmonth
doaj +1 more source
Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition
Molecular Oncology, EarlyView.We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li +10 more
wiley +1 more source
MODELLING 2X2 CROSS-OVER DESIGNS WITH CARRY-OVER EFFECT FOR BINARY RESPONSES
Journal of Research in Medical Sciences, 2003 In Parallel designs which each patient receives only one treatment we need a large number of patients for assessing treatment effects. Cross-over trials are Known as longitudinal studies.In cross-over trials each patient is his or her own control and ...
H JAHANI HASHEMI +4 more
doaj
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
Cross-over versus sequential study design [PDF]
American Journal of Hypertension, 1996 M MYERS +7 more
openaire +1 more source
An Exploration of Technology Diffusion [PDF]
We develop a model that, at the aggregate level, is similar to the one sector neoclassical growth model, while, at the disaggregate level, has implications for the path of observable measures of technology adoption.
Bart Hobijn, Diego A. Comin
core
Properties of the Lambda(1405) Measured at CLAS
, 2011 The nature of the Lambda(1405), and its place in the baryon spectrum has remained uncertain for decades. Theoretical studies have shown that it may possess strong dynamical components which are not seen in other well-known baryons.
Moriya, Kei, Schumacher, Reinhard
core +2 more sources
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Molecular Oncology, EarlyView.This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source