Results 91 to 100 of about 6,986,470 (307)

Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells

open access: yesFEBS Letters, EarlyView.
Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López   +2 more
wiley   +1 more source

Inequality and Trust [PDF]

open access: yes
This paper reviews the literature on economic inequality and trust. Cross-country studies, within-country studies, and experiments all suggest that economic inequality exerts a negative influence on trust.
Jordahl, Henrik
core  

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Using Fractionalization Indexes: deriving methodological principles for growth studies from time series evidence [PDF]

open access: yes
Recent cross country growth studies have found that ethnolinguistic fractionalization is an important explanatory variable of long-run growth performance.
J.M. Luiz   +2 more
core   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Fifteen-Year Prospective Analysis of Television Viewing and Adiposity in African American and Caucasian Men and Women

open access: yesSAGE Open, 2015
There are limited data from long-term prospective studies on the association between television (TV) viewing and obesity. We investigated this association between TV viewing and body mass index (BMI) and waist circumference (WST) over 15 years on 3,269 ...
Chung-Yu Chen   +9 more
doaj   +1 more source

Knowledge and beliefs about the Red Cross: Perspectives of community members and Red Cross workers in San Ramón, Alajuela, Costa Rica

open access: yesCuadernos de investigación UNED, 2016
In Costa Rica, the Red Cross provides most pre-hospital emergency care and transport. Very few studies have investigated extra-hospital emergency care in Costa Rica so this study aimed to fill this gap through interviews with community members, surveys ...
Tela Ebersole, Anabelle Alfaro Obando
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

The Reciprocal Relationship Between Gratitude and Life Satisfaction: Evidence From Two Longitudinal Field Studies

open access: yesFrontiers in Psychology, 2019
Gratitude and life satisfaction are associated with several indicators of a good life (e.g., health, pro-social behavior, and relationships). However, how gratitude and life satisfaction relate to each other over time has remained unknown until now ...
Wenceslao Unanue   +7 more
doaj   +1 more source

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