Results 81 to 90 of about 26,651,677 (294)

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Wally and the Major [picture] : going over his head /

open access: yes, 1964
Part of the Stan Cross Archive of cartoons and drawings, 1912-1974.; Inscription: "Stan Cross 4/275"--In ink, lower right. "7580 Fri Nov 13 Going Over His Head"--In ink, right margin; "7580"--In pencil, upper right corner.; Also available in an ...
Cross, Stan, 1888-1977.
core  

The Reciprocal Relationship Between Gratitude and Life Satisfaction: Evidence From Two Longitudinal Field Studies

open access: yesFrontiers in Psychology, 2019
Gratitude and life satisfaction are associated with several indicators of a good life (e.g., health, pro-social behavior, and relationships). However, how gratitude and life satisfaction relate to each other over time has remained unknown until now ...
Wenceslao Unanue   +7 more
doaj   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

"Come on Jonathan he'll soon get over it", with reference to World War 1 [picture] /

open access: yes, 1917
Part of the Stan Cross Archive of cartoons and drawings, 1912-1974.; Inscription: "Stan Cross"--In ink, lower right. "John Bull "Come on Jonathan; he'll soon get over it" John Bull "It's a thing that always happens in revolutions Jonathan, he will fight ...
Cross, Stan, 1888-1977.
core  

Fundamentos y aplicaciones del diseño de casos cruzados Case-crossover design: Basic essentials and applications

open access: yesGaceta Sanitaria, 2009
El diseño de casos cruzados es un diseño epidemiológico observacional propuesto por Maclure en 1991 para valorar si alguna exposición intermitente o inusual ha desencadenado un evento agudo a muy corto plazo.
Eduardo Carracedo-Martínez   +4 more
doaj  

Longitudinal and Cross-Sectional Studies to Evaluate Changes in Cow Milk Microbiota Over the Lactation Stages

open access: yesActa Veterinaria
To clarify the changes in milk microbiota by lactation stage, i.e., d ays in milk (DIM) for Fresh of 0 to 21, Early (DIM of 22 to 80), Middle (DIM of 81 to 200), and Late (DIM 201 or more) lactation stages in dairy cows, we performed longitudinal (12 ...
Shinozuka Yasunori   +7 more
doaj   +1 more source

Cross-national research on adolescent mental health: a systematic review comparing research in low, middle and high-income countries

open access: yesBMJ Global Health
Background Although 90% of the global adolescent population resides in low and middle-income countries (LMICs), cross-national mental health research has primarily focused on high-income countries.
Xiao Zhang   +14 more
doaj   +1 more source

The problem of cross‐over design in airway studies [PDF]

open access: yesAnaesthesia, 2009
Greif, Robert, Theiler, Lorenz
openaire   +2 more sources

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

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