Results 81 to 90 of about 10,849,876 (337)

What Comes First Metacognition or Negative Emotion? A Test of Temporal Precedence

open access: yesFrontiers in Psychology, 2019
The Self-Regulatory Executive Function model predicts that emotional symptoms and metacognition can causally affect each other. Crucially, for the model metacognition must cause emotion disorder symptoms. Therefore, in time-series data involving repeated
Lora Capobianco   +5 more
doaj   +1 more source

Proton pump inhibitors and vascular function: A prospective cross-over pilot study

open access: yesVascular Medicine, 2015
Proton pump inhibitors (PPIs) are commonly used drugs for the treatment of gastric reflux. Recent retrospective cohorts and large database studies have raised concern that the use of PPIs is associated with increased cardiovascular (CV) risk.
Yohannes T. Ghebremariam   +7 more
semanticscholar   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Trend-resistant and cost-efficient cross-over designs for mixed models. [PDF]

open access: yes
A mixed model approach is used to construct optimal cross-over designs. In a cross-over experiment the same subject is tested at different points in time.
Tack, L, Vandebroek, Martina
core  

Famennian (Upper Devonian) conodont zonation: revised global standard. [PDF]

open access: yes, 2017
The revision of the Famennian part of the “Late Devonian Standard Conodont Zonation” is based on the in-equivalence between biozones and time, and the rejection of the presumed single phyletic concept on which the previous zonation was based.
M.C. Perri   +10 more
core   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

A cross-border approach to mental health promotion.

open access: yes, 2012
This paper reports on preliminary findings from a project commissioned by the Centre for Cross Border Studies, Armagh. The project is concerned with cross border co-operation in the development of mental health promotion in the North and South of Ireland,
Barry, Margaret M., Friel, Sharon
core  

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

Effect of Electronic Moxibustion in Patients with IDH: A Randomized Crossover Pilot Study

open access: yesInternational Journal of General Medicine
Tai-Jan Liu,1,2 Heng-Chih Pan,3– 6 Chin-Chan Lee,3,4,6 Chun-Yu Chen,3,4,6 I-Wen Wu,3,7,8 Chiao-Yin Sun,3,4 Kuo-Su Chen,3,4 Heng-Jung Hsu,3,4,6 Yih-Ting Chen,3,4 Cheng-Kai Hsu,3,4 Yuan-Chieh Yeh1,9 1Department of Traditional Chinese Medicine, Keelung ...
Liu TJ   +10 more
doaj  

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

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