Results 101 to 110 of about 10,849,876 (337)

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Methodological problems in cross-country analyses of economic growth [PDF]

Many cross country studies have been conducted over the last twenty years to explain how various factors affect economic growth rates in the developing countries.
Azam, Jean-Paul, Guillaumont, Sylviane
core  

Longitudinal and Cross-Sectional Studies to Evaluate Changes in Cow Milk Microbiota Over the Lactation Stages

Acta Veterinaria
To clarify the changes in milk microbiota by lactation stage, i.e., d ays in milk (DIM) for Fresh of 0 to 21, Early (DIM of 22 to 80), Middle (DIM of 81 to 200), and Late (DIM 201 or more) lactation stages in dairy cows, we performed longitudinal (12 ...
Shinozuka Yasunori, Suzuki Naoki, Kitsukawa Manabu, Hayashi Mayu, Suenaga Nagomu, Shimizu Yuko, Kurumisawa Tomomi, Kawai Kazuhiro   +7 more
doaj   +1 more source

Cross-national research on adolescent mental health: a systematic review comparing research in low, middle and high-income countries

BMJ Global Health
Background Although 90% of the global adolescent population resides in low and middle-income countries (LMICs), cross-national mental health research has primarily focused on high-income countries.
Xiao Zhang, Anne Abio, David M Ndetei, Samir Kumar Praharaj, Wan Mohd Azam Wan Mohd Yunus, Yuko Mori, Zahra Kafami Khorasani, Sonja Gilbert, Meytal Grimland, Nikita Bezborodovs, Sanju Silwal, Minja Westerlund, Hitoshi Kaneko, Emmi Heinonen, Andre Sourander   +14 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

The problem of cross‐over design in airway studies [PDF]

Anaesthesia, 2009
Greif, Robert, Theiler, Lorenz
openaire   +2 more sources

Fundamentos y aplicaciones del diseño de casos cruzados Case-crossover design: Basic essentials and applications

Gaceta Sanitaria, 2009
El diseño de casos cruzados es un diseño epidemiológico observacional propuesto por Maclure en 1991 para valorar si alguna exposición intermitente o inusual ha desencadenado un evento agudo a muy corto plazo.
Eduardo Carracedo-Martínez, Aurelio Tobías, Marc Saez, Margarita Taracido, Adolfo Figueiras   +4 more
doaj  

3D printing vs traditional workflow for the fabrication of mandibular implant overdentures: study protocol for a mixed-methods cross-over RCT

Trials
Background Complete tooth loss is a significant global oral health issue, particularly impacting older individuals with lower socioeconomic status. Computer-assisted technologies enhance oral healthcare access by the elderly.
Dana Jafarpour, Nesma El-Amier, Jocelyne Feine, Christophe Bedos, Samer Abi-Nader, Shahrokh Esfandiari, Tibor Shuster, Elizabeth Zimmermann, Raphael de Souza   +8 more
doaj   +1 more source

Validation for the Reduced Western Ontario and McMaster Universities Osteoarthritis Index Function Scale

Journal of Orthopaedic Surgery, 2008
Purpose. To assess the criterion validity, repeatability, and the missing value protocol of the reduced Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) function scale (‘reduced scale’). Methods.
SL Whitehouse, RW Crawford, ID Learmonth
doaj   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source