Results 151 to 160 of about 2,115,171 (296)

Understanding and measuring mechanical signals in the tumor stroma

FEBS Open Bio, EarlyView.
This review discusses cancer‐associated fibroblast subtypes and their functions, particularly in relation to extracellular matrix production, as well as the development of 3D models to study tumor stroma mechanics in vitro. Several quantitative techniques to measure tissue mechanical properties are also described, to emphasize the diagnostic and ...
Fàtima de la Jara Ortiz, Chiara Cimmino, Maurizio Ventre, Alessandra Cambi   +3 more
wiley   +1 more source

Macrolide resistance mechanisms among Streptococcus pneumoniae isolated over 6 years of Canadian Respiratory Organism Susceptibility Study (CROSS) (1998 2004) [PDF]

, 2007
Aleksandra Wierzbowski, Kimberly A. Nichol, Nancy M. Laing, Tamiko Hisanaga, A. Nikulin, James A. Karlowsky, D. J. Hoban, George G. Zhanel   +7 more
openalex   +1 more source

Beyond digital twins: the role of foundation models in enhancing the interpretability of multiomics modalities in precision medicine

FEBS Open Bio, EarlyView.
This review highlights how foundation models enhance predictive healthcare by integrating advanced digital twin modeling with multiomics and biomedical data. This approach supports disease management, risk assessment, and personalized medicine, with the goal of optimizing health outcomes through adaptive, interpretable digital simulations, accessible ...
Sakhaa Alsaedi, Xin Gao, Takashi Gojobori   +2 more
wiley   +1 more source

A randomized, placebo-controlled, cross-over study of ginger extracts and Ibuprofen in osteoarthritis

, 2000
Henning Bliddal, A. Rosetzsky, P. Schlichting, Morten Sloth Weidner, L. Agerskov Andersen, H.-H Ibfelt, Kyle S. Christensen, O N Jensen, J Barslev   +8 more
openalex   +1 more source

AKL1, a botanical mixture for the treatment of asthma: a randomised, double-blind, placebo-controlled, cross-over study [PDF]

, 2007
Mike Thomas, Jane Sheran, Natalie Smith, Sofia Fonseca, Amanda Lee   +4 more
openalex   +1 more source

Bioengineering facets of the tumor microenvironment in 3D tumor models: insights into cellular, biophysical and biochemical interactions

FEBS Open Bio, EarlyView.
The tumor microenvironment is a dynamic, multifaceted complex system of interdependent cellular, biochemical, and biophysical components. Three‐dimensional in vitro models of the tumor microenvironment enable a better understanding of these interactions and their impact on cancer progression and therapeutic resistance.
Salma T. Rafik, Deniz Bakkalci, Alexander J. MacRobert, Umber Cheema   +3 more
wiley   +1 more source

Effects of oral adenosine 5'-triphosphate and adenosine in enteric-coated capsules on indomethacin-induced permeability changes in the human small intestine: a randomized cross-over study [PDF]

, 2007
Martijn J.L. Bours, Hilde J Bos, Jon Meddings, Robert J. Brummer, Piet A. van den Brandt, Pieter C. Dagnelie   +5 more
openalex   +1 more source

On subcellular distribution of the zinc finger 469 protein (ZNF469) and observed discrepancy in the localization of endogenous and overexpressed ZNF469

FEBS Open Bio, EarlyView.
ZNF469 regulates the expression of genes encoding extracellular matrix proteins. Endogenous ZNF469 is predominantly cytoplasmic, while in transfected cells, it forms aggregates reminiscent of biomolecular condensates, located mainly in the nucleus. These condensates exhibit overlapping staining with proteasomes and are also associated with the mitotic ...
Anne Elisabeth Christensen Mellgren, Ileana Cristea, Thomas Stevenson, Endy Spriet, Per Morten Knappskog, Stig Ove Bøe, Harald Kranz, Sushma N. Grellscheid, Eyvind Rødahl   +8 more
wiley   +1 more source

Premenopausal women affected by sexual arousal disorder treated with sildenafil: a double‐blind, cross‐over, placebo‐controlled study

, 2001
Salvatore Caruso, Giorgia Intelisano, Lorenzo Lupo, Carmela Agnello   +3 more
openalex   +1 more source

Effectiveness of low-dose doxycycline (LDD) on clinical symptoms of Sjögren's Syndrome: a randomized, double-blind, placebo controlled cross-over study [PDF]

, 2007
Hubertus Seitsalo, Raija K. Niemelä, Magdalena Marinescu‐Gava, Tuija Vuotila, Leo Tjäderhane, Tuula Salo   +5 more
openalex   +1 more source