Results 91 to 100 of about 6,863,210 (309)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Emergence of new resistances to Cydia pomonella Granulovirus: insights from 12 years of monitoring

open access: yesFrontiers in Physiology
IntroductionCodling moth resistance to the granulosis virus CpGV, a widely adopted biological control agent in apple orchards poses a significant challenge for growers.
Myriam Siegwart   +3 more
doaj   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Convergent adaptive architectures linking chemoresistance and radioresistance in chemoradiotherapy: a systems-level perspective

open access: yesFrontiers in Oncology
BackgroundChemoradiotherapy (CRT) remains a cornerstone of treatment for multiple solid malignancies; however, durable disease control is frequently limited by the emergence of resistance. While chemoresistance and radioresistance have traditionally been
Xudong Yi   +16 more
doaj   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

Aneuploidy underlies brefeldin A-induced antifungal drug resistance in Cryptococcus neoformans

open access: yesFrontiers in Cellular and Infection Microbiology
Cryptococcus neoformans is at the top of the list of “most wanted” human pathogens. Only three classes of antifungal drugs are available for the treatment of cryptococcosis.
Zhi-hui Zhang   +9 more
doaj   +1 more source

Chlorantraniliprole selection, synergism and cross-resistance to various insecticides in tomato pinworm, Tuta absoluta (Meyrick) [PDF]

open access: yesنامه انجمن حشره‌شناسی ایران
Tuta absoluta is an invasive polyphagous pest recently reported on tomato, brinjal, and potato in India. It has acquired resistance to many chemical insecticides under field control.
Ranganathan Muthusamy   +5 more
doaj   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Detection of KPC-216, a Novel KPC-3 Variant, in a Clinical Isolate of Klebsiella pneumoniae ST101 Co-Resistant to Ceftazidime-Avibactam and Cefiderocol

open access: yesAntibiotics
Background: Carbapenemase-producing Klebsiella pneumoniae (CP-KP) represents a global threat to public health, with limited antimicrobial therapeutic options. In this study, we analyzed a ceftazidime/avibactam (CAZ-AVI)-resistant K.
Maria Giufrè   +8 more
doaj   +1 more source

cross-resistance

open access: yes
Citation: 'cross-resistance' in the IUPAC Compendium of Chemical Terminology, 5th ed.; International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.14560 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms.
openaire   +1 more source

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