Results 51 to 60 of about 942,688 (340)

A systematic review of platinum and taxane resistance from bench to clinic: an inverse relationship [PDF]

open access: yes, 2007
We undertook a systematic review of the pre-clinical and clinical literature for studies investigating the relationship between platinum and taxane resistance.
Davey, Ross   +2 more
core   +1 more source

Novel Genetic Risk Factor Identified for L‐Asparaginase‐Induced Pancreatitis in Pediatric Patients With Cancer

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background L‐asparaginase is a critical component in treatment protocols for pediatric acute lymphoblastic leukemia. Acute pancreatitis reactions can necessitate delays and, in some cases, discontinuation of L‐asparaginase, which compromises outcomes.
Edward J. Raack   +39 more
wiley   +1 more source

A Newer In Vitro Model for the Study of Development of in vitro resistance to penicillin in a novel isolate of Streptococcus tigurinus

open access: yesJournal of Microbiology and Infectious Diseases, 2017
Objectives: Streptococcus tigurinus is a new member of the Streptococcus mitis group. It causes various invasive infections. Its isolation from the oral cavity has been reported recently for the first time in our previous study.
Shree Dhotre   +4 more
doaj   +1 more source

Effects of LPS Composition in Escherichia coli on Antibacterial Activity and Bacterial Uptake of Antisense Peptide-PNA Conjugates

open access: yesFrontiers in Microbiology, 2022
The physical and chemical properties of the outer membrane of Gram-negative bacteria including Escherichia coli have a significant impact on the antibacterial activity and uptake of antibiotics, including antimicrobial peptides and antisense peptide ...
Lise Goltermann   +6 more
doaj   +1 more source

Understanding cisplatin resistance using cellular models [PDF]

open access: yes, 2007
Many mechanisms of cisplatin resistance have been proposed from studies of cellular models of resistance including changes in cellular drug accumulation, detoxification of the drug, inhibition of apoptosis and repair of the DNA adducts.
Davey, Mary W., Stordal, Britta
core   +2 more sources

Upacicalcet: A Novel Intravenous Calcimimetic Agent for Patients Undergoing Hemodialysis With Secondary Hyperparathyroidism

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Secondary hyperparathyroidism (SHPT) is a common complication in patients receiving maintenance dialysis, driven by calcium and phosphate metabolism disturbances. Calcimimetics are central to the management of SHPT by enhancing calcium‐sensing receptor sensitivity and reducing parathyroid hormone secretion.
Fumihiko Koiwa   +3 more
wiley   +1 more source

Enterocin Cross-Resistance Mediated by ABC Transport Systems

open access: yesMicroorganisms, 2021
In their struggle for life, bacteria frequently produce antagonistic substances against competitors. Antimicrobial peptides produced by bacteria (known as bacteriocins) are active against other bacteria, but harmless to their producer due to an associated immunity gene that prevents self-inhibition.
Claudia Teso-Pérez   +6 more
openaire   +6 more sources

Mechanisms of cross and multiple herbicide resistance in Alopecurus myosuroides and Lolium rigidum [PDF]

open access: yes, 1994
L’Alopecurus myosuroides et le Lolium rigidum ont développé des résistances croisées et multiples à des herbicides ayant différents modes d'action et provenant de diverses classes chimiques.
Hall, L.M., Powles, S.B., Tardif, F.J.
core   +1 more source

Adjunctive Therapeutic Plasma Exchange in Refractory Adult‐Onset Still's Disease Complicated by Secondary Macrophage Activation Syndrome: A Single‐Center Experience

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Adult‐onset Still's disease (AOSD) complicated by macrophage activation syndrome (MAS) carries substantial mortality. The role of therapeutic plasma exchange (TPE) remains uncertain. Methods We retrospectively analyzed patients with AOSD‐MAS treated with TPE at a single‐center.
Masataka Ueda   +15 more
wiley   +1 more source

A Novel Bioimpedance-Based Detection of Miltefosine Susceptibility Among Clinical Leishmania donovani Isolates of the Indian Subcontinent Exhibiting Resistance to Multiple Drugs

open access: yesFrontiers in Cellular and Infection Microbiology, 2021
The extent of susceptibility towards miltefosine (Mil), amphotericin B (AmpB), and paromomycin (Paro) was measured among 19 clinical isolates of Leishmania donovani (LD).
Souradeepa Ghosh   +12 more
doaj   +1 more source

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