Results 91 to 100 of about 2,803,084 (343)

A Nonlinear Panel Data Model of Cross-Sectional Dependence [PDF]

open access: yes
This paper proposes a nonlinear panel data model which can generate endogenously both `weak' and `strong' cross-sectional dependence. The model's distinguishing characteristic is that a given agent's behaviour is influenced by an aggregation of the views
George Kapetanios   +2 more
core  

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

How Does the Market Value Unfunded Pension Liabilities? [PDF]

open access: yes
We lead off by discussing a number of theoretical reasons for expecting various relationships between a firm's unfunded pension liability and its market value. We then discuss our doubts about the methodology of earlier papers which studied the empirical
Jeremy I. Bulow   +2 more
core  

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

A nationwide epidemiological sample survey on cerebrovascular disease in China

open access: yesChinese Journal of Contemporary Neurology and Neurosurgery, 2018
Cerebrovascular disease leads to serious disease burden because of its high morbidity, disability and mortality. In recent years, its prevalence, incidence and mortality showed a downward trend in most high-income countries but in low and middle income ...
Hai-xin SUN, Wen-zhi WANG
doaj  

Epidemiological profile of patients treated at the Cornea's Department of the Reference Center in Ophthalmology, Goiás, Brazil [PDF]

open access: yesRevista Brasileira de Oftalmologia
Objective: To describe the epidemiological profile of corneal disorders diagnosed in the Corneal Department of the Ophthalmology Reference Center, Universidade Federal de Goiás, between 2009 and 2018.
Fernanda Mendonça Galvão   +8 more
doaj   +1 more source

Study design III: Cross-sectional studies [PDF]

open access: yesEvidence-Based Dentistry, 2006
In this series, I previously gave an overview of the main types of study design and the techniques used to minimise biased results. Here, I describe cross-sectional studies, their uses, advantages and limitations.
openaire   +2 more sources

What's the best test for HSV-2 after exposure? [PDF]

open access: yes, 2007
Enzyme-linked immunosorbent assay (ELISA ) tests based on herpes simplex virus 2's (HSV -2) glycoprotein G have demonstrated high sensitivity and specificity in determining seropositivity for HSV-2 antibodies (strength of recommendation [SOR]: C, based ...
Heintzman, John   +2 more
core  

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

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