Results 71 to 80 of about 1,589,263 (300)

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

Observational (cross-sectional and longitudinal) studies

, 2018
The chapter explores observational studies and their application in physical activity research with a particular focus on cross-sectional and longitudinal approaches. Considerations in the design and use of both types of studies are considered and the
Christopher Gidlow, Owens, Christopher S, Crone, Diane, David V.B. James, Gidlow, Christopher, James, David V, Diane Crone, Christopher S. Owens   +7 more
core   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

Characteristics of the different cross-sectional studies.

, 2019
Characteristics of the different cross-sectional studies.
Xinlan Xu (1552288), Lan Qin (1678855), Weide Li (7372601), Qishan Wei (7372604), Guowei Yu (584058), Wenjiao Yang (4517623)   +5 more
core   +1 more source

Oral health behavior patterns among Tanzanian university students:a repeat cross-sectional survey [PDF]

, 2001
Purpose: This study examines oral health behavioral trends and the development of\ud sociodemographic differences in oral health behaviors among Tanzanian students between 1999\ud and 2000.\ud Methods: The population targeted was students attending the ...
Åstrøm, A.N., Astrom Nordrehaug, Anne, Masalu, J.R., Masalu Rose, Joyce   +3 more
core   +1 more source

Perceived barriers by university students in relation the leisure-time physical activity. http://dx.doi.org/10.5007/1980-0037.2013v15n2p164

Revista Brasileira de Cineantropometria e Desempenho Humano, 2013
To estimate the prevalence and socio-demographic indicators and program affiliation associated with the perceived barriers for physical activity practice; and, to analyze the association between the perceived barriers with leisure-time physical ...
Thiago Ferreira de Sousa, Silvio Aparecido Fonseca, Aline Rodrigues Barbosa   +2 more
doaj  

Association between family structure, maternal education level, and maternal employment with sedentary lifestyle in primary school-age children

Jornal de Pediatria (Versão em Português), 2013
Objective: : To determine the association between family structure, maternal education level, and maternal employment with sedentary lifestyle in primary school-age children. Method: : Data were obtained from 897 children aged 6 to 12 years.
Francisco Vázquez-Nava, Norberto Treviño-Garcia-Manzo, Carlos F. Vázquez-Rodríguez, Eliza M. Vázquez-Rodríguez   +3 more
doaj   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

A Monte Carlo Evaluation of Some Common Panel Data Estimators when Serial Correlation and Cross-sectional Dependence are Both Present [PDF]

This study employs Monte Carlo experiments to evaluate the performances of a number of common panel data estimators when serial correlation and cross-sectional dependence are both present.
W. Robert Reed, Haichun Ye
core