Results 31 to 40 of about 251,458 (268)

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Forestry Bioeconomy Contribution on Socioeconomic Development: Evidence from Greece

open access: yesLand, 2022
Forests are of utmost importance for sustainability because of their ongoing contributions to biodiversity protection, fertility management in agricultural areas, and the well-being of people.
Stavros Kalogiannidis   +3 more
doaj   +1 more source

Cross-border acquisitions [PDF]

open access: yes, 2008
Chapter Objectives: - Highlights the motivations for cross-border acquisitions - Provides an overview of trends in cross-border acquisitions - Highlights the empirical evidence on cross-border acquisitions - Highlights the issues in cross-border ...
Vishwanath, S. R.   +1 more
core  

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

Enhancing cross-border disaster management in the Balkans: a framework for collaboration part I

open access: yesJournal of Innovation and Entrepreneurship
This abstract presents the methodological approach employed in a comprehensive study focusing on decision making in a collaborative manner in disaster management, with a specific emphasis on cross-border disasters in the Balkan region.
Despoina Kanteler, Ioannis Bakouros
doaj   +1 more source

Plate Food Waste in Early Childhood Education: Contextual and Nutritional Drivers with Implications for Sustainable Food Systems

open access: yesFoods
Plate food waste (PFW) in early childhood education is a critical yet understudied issue in Eastern Europe, with implications for nutrition, sustainability, and food security.
Dimitrie Stoica   +6 more
doaj   +1 more source

Cross Border Tourism and Regional Development: Case Indonesia-Timor Leste Cross Border

open access: yesEkuilibrium: Jurnal Ilmiah Bidan Ilmu Ekonomi, 2020
This study aims to: (i) describe the perception of stakeholder about cross border tourism in Wini Indonesia and the Oecusse-timor Leste, (ii) analyze the impact of cross border tourism on the regional development.
Werenfridus Taena, Felisisima Afoan
doaj   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

Hump-Shaped Cross-Price Effects and the Extensive Margin in Cross-Border Shopping

open access: yes, 2022
This paper examines the effect of cross-border shopping on grocery demand in Norway using monthly store x category sales data from Norway's largest grocery chain 2012-2016.
Ulsaker, Simen A.,   +2 more
core   +1 more source

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