Results 51 to 60 of about 251,458 (268)

The Maximum Principle for Variable-Order Fractional Diffusion Equations and the Estimates of Higher Variable-Order Fractional Derivatives

open access: yesFrontiers in Physics, 2020
In this paper, the maximum principle of variable-order fractional diffusion equations and the estimates of fractional derivatives with higher variable order are investigated.
Guangming Xue   +5 more
doaj   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Digital Storytelling and Cultural Identity in Romanian Memetic Discourse

open access: yesHumanities
This article examines Romanian internet memes as cultural micro-narratives that encode social critique, identity negotiation, and emotional response through compressed, multimodal storytelling.
Alexandra-Monica Toma   +1 more
doaj   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Cross-border solidarity in the Greater Region SaarLorLux. The example of the crossborder labour market [PDF]

open access: yes
Due to the pandemic-related border closures within the European Union (EU) in spring 2020, freedom of movement has been temporarily restricted in some parts of the Schengen area.
FUNK, Ines   +2 more
core  

Quality requirements for cross-border care in Europe: a qualitative study of patients', professionals' and healthcare financiers' views. [PDF]

open access: yes, 2009
BACKGROUND: In the past decade the issue of patient mobility has emerged on the European health policy agenda. Although the volume of patients crossing borders to obtain healthcare is low, it is increasing continuously and, due to its legal, financial ...
Vallejo, P   +13 more
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

open access: yesMolecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel   +6 more
wiley   +1 more source

CHIKV mRNA vaccines encoding conserved structural/envelope proteins confer broad cross-lineage protection against infection

open access: yesSignal Transduction and Targeted Therapy
With the broad spread of the chikungunya virus (CHIKV), there is an increasing demand for more effective and broadly protective vaccines. Here, we designed CHIKV mRNA vaccines containing full-length structural proteins or part of structural proteins ...
Xiaoming Liang   +24 more
doaj   +1 more source

A cross-border approach to mental health promotion.

open access: yes, 2012
This paper reports on preliminary findings from a project commissioned by the Centre for Cross Border Studies, Armagh. The project is concerned with cross border co-operation in the development of mental health promotion in the North and South of Ireland,
Barry, Margaret M., Friel, Sharon
core  

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