Results 91 to 100 of about 1,105,274 (313)
Cross-flow microfiltration of protein/polysaccharide mixture
碩士本研究以平板式掃流微過濾探討多醣體與蛋白質之分離純化。以孔徑0.025 micrometer之醋酸纖維濾膜,在pH=7下,過濾分子量為67 kDa的牛血清蛋白(BSA)與2000 kDa之葡聚醣(Dextran),探討在不同的掃流速度與過濾壓差下,過濾速度、過濾阻力、物質的阻擋率與薄膜結垢情形。 研究結果顯示,過濾牛血清蛋白與葡聚醣雙成分懸浮液時,掃流速度愈大,濾速也會愈快。增加過濾壓差時,濾速會上升,但過濾阻力也會顯著增加。牛血清蛋白與葡聚醣會在膜面上形成可逆及不可逆的結垢層 ...
司盼妤; Sz, Pan-yu
core
Computational analysis of a cross flow turbine performance
In the electrical energy generation context in Colombia, the water resources represent the 64% of the potential generated according to UPME in the 2015 year; becoming into a solution to the growing energy demand and to the supply of energy in non ...
Gómez Vanessa Ruiz +2 more
doaj +1 more source
MITF maintains genome stability in nonmelanocyte lineages
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
An improved turbulent boundary layer inflow condition, applied to the simulation of jets in cross-flow [PDF]
The jet acting perpendicular to a cross-flow boundary layer is a commonly studied complex turbulent flow. Our research was motivated by their potential application in separation delay devices, where jets can be used to produce streamwise vortices in a ...
Jewkes, James
core
The predicting equations for mass transfer rate in cross-flow rectangular dialyzers with double flow and recycle, have been derived by mass balances. The recycling operation has two conflicting effects.
葉和明; Yeh, Ho-ming
core +1 more source
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Removal of silver from wastewater using cross flow microfiltration
Removal of silver from wastewater was investigated using continuous cross flow microfiltration (MF) technique hollow fiber membranes with a pore size 0.2μm, with sorbent coated material Al2O3/SDSH2Dz particle size (8 μm).
Zanain M., Lovitt R.
doaj +1 more source
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source

