Results 91 to 100 of about 8,915,614 (369)

Predictors of anemia in preschool children: Biomarkers Reflecting Inflammation and Nutritional Determinants of Anemia (BRINDA) project. [PDF]

, 2017
Background: A lack of information on the etiology of anemia has hampered the design and monitoring of anemia-control efforts.Objective: We aimed to evaluate predictors of anemia in preschool children (PSC) (age range: 6-59 mo) by country and infection ...
Aaron, Grant J, Addo, O Yaw, Engle-Stone, Reina, Huang, Jin, Macdonald, Barbara, Namaste, Sorrel Ml, Peerson, Janet M, Rayco-Solon, Pura, Rohner, Fabian, Suchdev, Parminder S, Temple, Victor, Varadhan, Ravi, Williams, Anne M, Wirth, James P   +13 more
core  

T cell engagement of cross-presenting microglia protects the brain from a nasal virus infection

Science immunology, 2020
Microglia protect the brain from an intranasal VSV infection by cross-presenting neuronal antigen to antiviral CD8+ T cells. Safeguarding the sense of smell Given the proximity of the olfactory bulb to the upper airways, it is surprising that viruses ...
E. A. Moseman, Alexa C. Blanchard, D. Nayak, D. McGavern   +3 more
semanticscholar   +1 more source

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

Molecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath, Irene A. George, Srikanth S. Manda, Prasanth Ariyannur, Ekta R. Dhawale, Raja Sekhar Kommu, Rajan Datar, Darshana Patil, Vinita Trivedi, Manisha Singh, Kumar Prabhash, Sewanti Limaye, Richa Chauhan, Prashant Kumar   +13 more
wiley   +1 more source

Clonality pattern assessed by ERIC-PCR and REP-PCR in extended-spectrum betalactamase- producing Escherichia coli and Klebsiella pneumoniae isolates from patients with nosocomial urinary tract infections. Hospital Regional Lambayeque, Peru

Horizonte Médico, 2018
Objective: To determine the clonality pattern assessed by ERIC-PCR and REP-PCR in extended-spectrum beta-lactamase (ESBL)-producing Escherichia coli and Klebsiella pneumoniae isolates from patients with urinary tract infections at the Hospital Regional
Kelly Lelia López-Ramírez, Kevin Colbert Díaz-Maldonado, Martha Arminda Vergara Espinoza, Olivia Santamaría- Veliz, Luis Miguel Serquén-López, Bustamante Canelo Olinda, Franco Ernesto León-Jimenez, Franklin-Rómulo Aguilar-Gamboa   +7 more
doaj   +1 more source

Nosocomial infections prevalence study in a Serbian university hospital [PDF]

Vojnosanitetski Pregled, 2009
Background/Aim. Nosocomial infections (NI) are a serious health problem resulting in an enormous burden of excess morbidity and mortality rates, and health care costs.
Ilić Milena, Marković-Denić Ljiljana
doaj   +1 more source

Canine Trypanosoma cruzi infection in the Bolivian Chaco [PDF]

, 2018
A cross-sectional study on Trypanosoma cruzi was carried out in 2013 to evaluate the role of dogs as possible source of infection for humans in two rural communities of the highly endemic Bolivian Chaco (Bartolo, Chuquisaca Department, n = 57 dogs; and ...
Bartoloni, Alessandro, Cancrini, Gabriella, Gabrielli, Simona, Gamboa, Herlan, Macchioni, Fabio, Rojas, Patricia, Rojo, David, Roselli, Mimmo, Spinicci, Michele, Totino, Valentina   +9 more
core   +2 more sources

A cross-talk between epithelium and endothelium mediates human alveolar–capillary injury during SARS-CoV-2 infection

Cell Death and Disease, 2020
COVID-19, caused by SARS-CoV-2, is an acute and rapidly developing pandemic, which leads to a global health crisis. SARS-CoV-2 primarily attacks human alveoli and causes severe lung infection and damage.
Peng Wang, Ronghua Luo, Min Zhang, Yaqing Wang, T. Song, Tingting Tao, Zhongyu Li, Lin Jin, Hongyi Zheng, Wenwen Chen, Mengqian Zhao, Yongtang Zheng, J. Qin   +12 more
semanticscholar   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

Infección invasiva por Candida spp. En pacientes inmunocomprometidos: Descripción de curso clínico experiencia diagnóstica, manejo y seguimiento en centro de alta complejidad

Infectio, 2020
Introduction: Candida spp. is the main cause of fungemia, whose incidence has increased in recent years. There are insufficient local data about this pathology.
Pablo Andrés Moncada
doaj   +1 more source

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

Molecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson, Anders Lade Nielsen, Boe Sandahl Sorensen   +2 more
wiley   +1 more source