Results 91 to 100 of about 10,178 (262)

The C‐terminal region of KIF26B is indispensable for nephron progenitor condensation and kidney formation in mice

open access: yesFEBS Open Bio, EarlyView.
KIF26B plays an important role in kidney development. We engineered mice lacking the C‐terminal region of KIF26B and found severe kidney defects, including bilateral renal agenesis, similar to full Kif26b knockout mice. The mutation disrupted nephron progenitor condensation and reduced Gdnf‐Wnt11 signaling, showing that the KIF26B C‐terminal region is ...
Yuta Yamamura   +19 more
wiley   +1 more source

Comparative Study Regarding Body Weight in Turcana and R1 German Blackheaded x Turcana yearling ewes

open access: yesScientific Papers Animal Science and Biotechnologies, 2023
Researches were carried out in a commercial sheep farm from Arad county, situated in western Romania. Yearling ewes, with their age ranging from 12 to 13 months were included in the trial. Two genotypes were considered, purebred indigenous Turcana (TA, n
Ioan Padeanu   +5 more
doaj  

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

open access: yesFEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová   +2 more
wiley   +1 more source

Growth and feed efficiency of Nordic Red Dairy Cattle, Holstein, and their F1 crossbreeds when limiting feed energy concentration in prepubertal heifers

open access: yesJournal of Dairy Science
: Milk production and overall dairy farm economics depend on rearing dairy heifers. This study investigated the presence of a genotype by environment interaction in Holstein (HOL), Nordic Red dairy cattle (RDC), and their F1 crossbreeds (HOL × RDC) when ...
K. Johansen   +5 more
doaj   +1 more source

Sheep Production System and Farmers' Perception towards Dorper Crossbred Lambs in Eastern Amhara, Ethiopia

open access: yesScientific Papers Animal Science and Biotechnologies, 2023
The study was conducted to assess the production system and farmers' perceptions of Dorper crossbreds in Eastern Amhara, Ethiopia. Data on the sheep production system and farmers' perceptions were collected using participatory rural appraisal in Kalu and
Mesfin Lakew   +2 more
doaj  

Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1

open access: yesFEBS Open Bio, EarlyView.
The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay   +2 more
wiley   +1 more source

Effects of Crossbreeding and Concentrates Feeding on Growth Rates of Goat Kids Reared under Highlands Conditions

open access: yesScientific Papers Animal Science and Biotechnologies, 2023
Aim of the current research was to evaluate the effects that crossbreeding and concentrates feeding have on growth performance of goat kids managed under pasture conditions of the Romanian highlands.
Maria Sauer   +5 more
doaj  

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

open access: yesFEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya   +2 more
wiley   +1 more source

Comparative Study Regarding Body Development in Turcana and F1 German Blackheaded x Turcana Yearling Ewes

open access: yesScientific Papers Animal Science and Biotechnologies, 2023
Researches were carried out in a commercial sheep farm from Arad County, situated in western Romania. Yearling ewes, with their age ranging from 12 to 13 months were included in the trial. Two genotypes were considered, purebred indigenous Turcana (TA, n
Ioan Pădeanu   +6 more
doaj  

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

open access: yesFEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim   +4 more
wiley   +1 more source

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