Results 71 to 80 of about 10,178 (262)

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

Crossbreeding for Egg Production

Poultry Science, 1952
Abstract SEVERAL experiments have been conducted for determining the effect of crossbreeding poultry on rate of growth Most of the investigators seem to be in general agreement that crossbreeding tends to improve growth and hatchability. None of the experiments has been conducted, however, to determine the effect of crossbreeding from the standpoint ...
E.W. Glazener, R.E. Comstock, W.L. Blow, R.S. Dearstyne, C.H. Bostian   +4 more
openaire   +1 more source

Crossbreeding: implications for dairy cow fertility and survival

Animal, 2014
In pasture-based seasonal calving systems, failure to become pregnant during the breeding season results in important economic losses as maximum profit is attained by minimising costs and increasing the proportion of grass in the diet of the lactating ...
F. Buckley, N. Lopez-Villalobos, B.J. Heins   +2 more
doaj   +1 more source

Translating whole‐genome doubling into precision medicine in cancer

Molecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

Impact of Agro-Byproduct Supplementation on Carcass Traits and Meat Quality of Hair Sheep and Wool × Hair Crossbreds Grazing on Fescue Pasture

Animals
The effects of breed type (purebred or crossbred) and supplementation of agro-byproducts on the growth, carcass characteristics, and meat quality of landrace hair (Barbados Blackbelly; BB and St. Croix; SX) lambs was evaluated.
Jung Hoon Lee, Stephan Wildeus, Dahlia O’Brien, Brou Kouakou   +3 more
doaj   +1 more source

Growth Performance and Milk Yield in Sahelian × Anglo-Nubian Goats Following Crossbreeding in the Semi-Arid Zone of Mali

Agricultura Tropica et Subtropica, 2012
The objective of this study was to evaluate the effect of crossbreeding Sahelian Goats (SG) with Anglo-Nubian (AN) bucks on growth performance of kids and milk production of does during the pre-weaning period. Forty four suckled and hand-milked does were
Shaker Momani Mohamed, Sanogo Souleymane, Coulibaly Dounanké, Al-Olofi Samer, Alkhewani Talal   +4 more
doaj   +1 more source

Effects of dam breed and dietary source of n-3 polyunsaturated fatty acids on the growth and carcass characteristics of lambs sourced from hill sheep flocks

Animal, 2011
The objectives of this study were to investigate the effect of dietary lipid source on the growth and carcass characteristics of lambs sourced from a range of crossbred hill ewes.
R.W. Annett, A.F. Carson, L.E.R. Dawson, D.J. Kilpatrick   +3 more
doaj   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

Effect of crossbreeding on egg quality, incubation, and hatching activities of the pure and reciprocal cross between the Sasso and Wassache chickens

Poultry Science
: Understanding the effect of crossbreeding on egg quality and incubation is essential for the selection of superior genetic combinations in breeding programs.
Joshua T. Dzungwe, Koffi Tozo, Christophe A.A.M. Chrysostome, Rachida A. Tankouano, Oyegunle E. Oke, Kokou Tona   +5 more
doaj   +1 more source

Conventional and Mixed Model Approach to Estimate Heterosis of the Growth Traits in Boer Goat’s Crossbred Offspring Populations

Caraka Tani: Journal of Sustainable Agriculture, 2019
Heterosis is often utilized as a success indicator in a crossbreeding program. It is defined as the deviation of the crossbred means relative to their parental breeds.
Nuzul Widyas, Sigit Prastowo, Tristianto Nugroho, Adi Ratriyanto   +3 more
doaj   +1 more source