Results 71 to 80 of about 20,705 (343)

Crossbreeding the Forgotten Tool [PDF]

open access: yes, 2005
Most ranchers know crossbreeding can increase output, but perhaps, don’t appreciate the potential 25% crossbred advantage in lifetime productivity of crossbred cows. Yes, you read that correctly; 25% crossbred advantage in lifetime productivity.
Gosey, Jim
core  

Insight into the current genomic diversity, conservation status and population structure of Tunisian Barbarine sheep breed

open access: yesFrontiers in Genetics
Local livestock breeds play a crucial role in global biodiversity, connecting natural and human-influenced environments and contributing significantly to ecosystem services.
Samira Giovannini   +6 more
doaj   +1 more source

Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology

open access: yesMolecular Oncology, EarlyView.
This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic   +15 more
wiley   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

open access: yesMolecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas   +16 more
wiley   +1 more source

Crossbreeding Systems and The Theory Behind Composite Breeds [PDF]

open access: yes, 1991
Crossbreeding serves the beef cattle industry as a tool to improve productivity through heterosis (hybrid vigor) and through complementarity (combining different breed strengths) to match genetic resources to various feed resources, climates, management ...
Gosey, James A,
core  

PANoptosis in the pathogenesis of myelodysplastic syndromes

open access: yesMolecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla   +4 more
wiley   +1 more source

Crossbreeding as a strategy in dairy cattle herds [Elektronisk resurs]

open access: yes, 2021
This thesis aimed to explore benefits of dairy crossbreeding at herd level and form recommendations for dairy farmers, advisors, and breeding companies.
Clasen, Julie,   +1 more
core  

Comparison of the longevity and lifetime performance of Scottish Blackface ewes and their crosses within hill sheep flocks

open access: yesAnimal, 2011
A study was undertaken to compare the longevity and lifetime lamb output of purebred Scottish Blackface (BF) ewes with a range of crossbred genotypes from Scottish BF dams. For up to five successive breeding seasons, 1143 Scottish BF, Swaledale × BF (SW ×
R.W. Annett   +5 more
doaj   +1 more source

Castration‐resistant prostate cancer cells are addicted to the high activity of cyclin‐dependent kinase 2

open access: yesMolecular Oncology, EarlyView.
We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee   +3 more
wiley   +1 more source

EC68-217 Selection and Crossbreeding for the Pork Producer [PDF]

open access: yes, 1968
Extension Circular 68-217: Selection and crossbreeding for the pork producer; introduction, crossbreeding information, systems of crossbreeding, single cross between two breeds, two breed cross, three-breed cross, breed selection, hybrid boars, selection
Lucas, Leo
core  

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