Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
Tres aproximaciones al mestizaje en América Latina colonial.
Based on the exploration of three approaches to crossbreeding in the colonial history of Latin America: Race Mixture in the History of Latin America by Magnus Mörner, El Mestizaje como Gesta by Juan Olaechea Labayen and El Pensamiento Mestizo by Serge ...
Paola Castaño Rodríguez.
doaj
Performance, methane production, and beef lipid profile of young bulls finished in feedlot [PDF]
The objective of this work was to evaluate the growth performance, enteric methane production, carcass traits, and fatty acid profile of the Longissimus thoracis muscle of young Nellore and Angus x Nellore beef bulls fed with a high-lipid diet and ...
Barbara Martins Rodrigues +5 more
doaj +1 more source
Sire Effects on Carcass of Beef-Cross-Dairy Cattle: A Case Study in New Zealand
There is interest in increasing the carcass value of surplus calves born in the dairy industry that are reared for beef production in New Zealand. This experiment evaluated the carcass of Angus and Hereford sires via progeny testing of beef-cross-dairy ...
Natalia Martín +5 more
doaj +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
RNA‐related functions of BRCA2 in transcription, replication, and genome stability
Beyond its role in homologous recombination, BRCA2 regulates R‐loop homeostasis, DNA–RNA hybrid resolution, RNA polymerase II dynamics, and transcriptional activation. Disruption of any of these functions can contribute to genome instability, inflammatory signaling, and tumorigenesis. BRCA2 is a central tumor suppressor protein best known for its roles
Lucia Alvaro‐Aranda +2 more
wiley +1 more source
Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley +1 more source
Dairy crossbreeding challenges the French dairy cattle sociotechnical regime
International audienceRotational crossbreeding can be faster and more effective than pure breeding in improving the functional traits of cows and developing robust dairy cattle systems. However, this practice remains uncommon worldwide.
Marie-Angélina Magne +3 more
core +1 more source
Amélioration des ovins dans l'Ouémé et le Plateau en République du Bénin. Enjeux de croisement des ovins Djallonké avec les moutons du Sahel [PDF]
Sheep Management in Oueme and Plateau Departments of Republic of Benin. Stakes of Djallonke Crossbreeding with Sahelian Sheep. The present study is a reflection through bibliographical review and on the current situation of sheep breeding in Oueme and ...
Salifou, S. +4 more
doaj

