Results 71 to 80 of about 44,076 (327)

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

Genetics of crossbreeding

, 2020
In pig and poultry breeding programs, animals from genetically distinct purebred breeding lines are mated to produce crossbred animals, which provide food products to consumers. Although the aim of such breeding programs is to improve the performance of the crossbreds, selection takes place in the purebred lines, and is usually based on purebred ...
openaire   +2 more sources

Estimates of crossbreeding parameters in a multibreed beef cattle crossbreeding project

South African Journal of Animal Science, 2000
Data from purebred and crossbred cattle, consisting of the Afrikaner (A), Simmentaler (S) and Hereford (H) breeds managed in a relatively intensive but high stocking rate environment, were analysed to estimate breed direct effects, individual heterotic effects, breed maternal and maternal heterotic effects for birth weight (BW) and weaning weight (WW).
Skrypzeck H., Schoeman S.J., Jordaan G.F., Neser F.W.C.   +3 more
openaire   +3 more sources

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

Molecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié, Umberto Malapelle, Catherine Alix‐Panabières, Claus Lindbjerg Andersen, Sandra Chlebowski, Vivien Lake, Caroline Lacoux, Virginie Lespinet‐Fabre, Olivier Bordone, Simon Heeke, Christophe Bontoux, Ellen Heitzer, Klaus Pantel, Paul Hofman   +13 more
wiley   +1 more source

Tres aproximaciones al mestizaje en América Latina colonial.

Historia Crítica, 2002
Based on the exploration of three approaches to crossbreeding in the colonial history of Latin America: Race Mixture in the History of Latin America by Magnus Mörner, El Mestizaje como Gesta by Juan Olaechea Labayen and El Pensamiento Mestizo by Serge ...
Paola Castaño Rodríguez.
doaj  

Slaughter and carcass characteristics, and meat quality in Holstein Friesian, Eastern Anatolian Red and crossbreed (F1) bulls fed at high altitude [PDF]

Journal of Central European Agriculture
The study aimed to determine the slaughter traits, carcass characteristics and meat quality of Eastern Anatolian Red (EAR), Holstein Friesian (HF) and their crossbreed (F1) bulls to provide a different systematic structure to red meat production for ...
Sadrettin Yüksel, Alpay Karaçuhalılar
doaj   +1 more source

Effects of the Breeding Strategy Beef-on-Dairy at Animal, Farm and Sector Levels

Animals, 2023
The decline in farm revenue due to volatile milk prices has led to an increase in the use of beef semen in dairy herds. While this strategy (“Beef-on-dairy” (BoD)) can have economic benefits, it can also lead to unintended consequences affecting animal ...
Rana Hamas Ahmed, Christin Schmidtmann, Julius Mugambe, Georg Thaller   +3 more
doaj   +1 more source

Research Progress [PDF]

, 1965
Cooperating with the United States Department of AgricultureIntroduction -- Developmental problems -- Fertilizers -- Forages -- Dairying -- Climate and light -- Grasses -- Cereals -- Potatoes -- Vegetables, fruit -- Weed control -- Water -- Plant ...

core  

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

Molecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola, Rafael Lopes Goncalves, Marin Truchi, Caroline Lacoux, Célia Scribe, Hugo Cadis, Laetitia Guardini, Sophie Bekisz, Marius Ilié, Paul Hofman, Georges Vassaux, Bernard Mari, Roger Rezzonico   +12 more
wiley   +1 more source