Results 121 to 130 of about 539,900 (289)

Extracellular vesicle lipidomics liquid biopsy reveals systemic and tumor microenvironment metabolic reprogramming in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani   +9 more
wiley   +1 more source

Simple Expression Domains Are Regulated by Discrete CRMs During Drosophila Oogenesis

open access: yesG3: Genes, Genomes, Genetics, 2017
Eggshell patterning has been extensively studied in Drosophila melanogaster. However, the cis-regulatory modules (CRMs), which control spatiotemporal expression of these patterns, are vastly unexplored.
Nicole T. Revaitis   +5 more
doaj   +1 more source

(Co-)fibration of generalized crossed modules

open access: yes
Crossed modules are algebraic structures that generalize the concept of group extensions. They involve group-like objects (often groups or groupoids) with additional structure and mappings between them that satisfy certain properties. Generalized crossed
GÜLSÜN AKAY, HATİCE
core   +1 more source

Relations between crossed modules of different algebras [PDF]

open access: yes, 2016
In the present work we extend to crossed modules the classical adjunction between the Liezation functor Liea : As Lie, which makes every associative algebra A into a Lie algebra via the bracket a,b ab ba , for all a,b A, and U : Lie As, which ...
Fernández Casado, Rafael
core  

Semi-complete crossed modules of lie algebras [PDF]

open access: yes, 2012
WOS: 000309362700016We investigate some sufficient and necessary conditions for (semi)-completeness of crossed modules in Lie algebras and we establish its relationships with the holomorphy of a crossed module.
Aytekin, A.   +5 more
core   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

open access: yesMolecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez   +5 more
wiley   +1 more source

On crossed modules in modified categories of interest

open access: yesMathematical Communications, 2016
Preliminary version, 19 ...
Uslu, Enver Onder   +2 more
openaire   +6 more sources

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

open access: yesMolecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault   +12 more
wiley   +1 more source

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

open access: yesMolecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu   +9 more
wiley   +1 more source

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso   +5 more
wiley   +1 more source

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