The underappreciated, underrecognized problem of fourth chromosome trisomy in <i>Drosophila melanogaster</i> stocks and a simple, general method for building diplo-4 stocks from triplo-4 stocks. [PDF]
Cook KR.
europepmc +1 more source
Objective The aim of this study was to apply sequence analysis (SA) to phenotype health care patterns of adult patients with musculoskeletal (MSK) conditions using primary care electronic health records and to investigate the association between these health care patterns and patients’ self‐reported outcomes after consultation.
Smitha Mathew+6 more
wiley +1 more source
The recombination landscape of introgression in yeast. [PDF]
Schwarzkopf EJ+2 more
europepmc +1 more source
Diverse Treatment Goals in Psoriatic Arthritis: Insights From Participants in the PARC Cohort
Objective The aim of this study was to examine patient‐reported treatment goals among individuals with psoriatic arthritis. Methods Participants in the Psoriatic Arthritis Research Consortium completed standardized assessments, including patient‐reported outcome (PROs) instruments, between 2017 and 2020.
Astia Allenzara+8 more
wiley +1 more source
Meta-analysis reveals that phenotypic plasticity and divergent selection promote reproductive isolation during incipient speciation. [PDF]
Jarrett BJM, Downing PA, Svensson EI.
europepmc +1 more source
As many patients with inflammatory arthritis (IA) have chronic pain, understanding how to best assess and manage pain in IA is a priority. Comorbid depression is prevalent in adults with IA, affecting 15% to 39% of people. Although pain and depression are thought to be associated in IA, this concept is largely based on cross‐sectional data.
Natasha Cox+3 more
wiley +1 more source
MalKinID: A classification model for identifying malaria parasite genealogical relationships using identity-by-descent. [PDF]
Wong W+10 more
europepmc +1 more source
Objective This study analyzed longitudinal trajectories of soluble Flt1 (sFlt1) levels, placenta growth factor (PlGF) levels, and sFlt1:PlGF ratios in a cohort of pregnant patients with systemic lupus erythematosus (SLE). Methods Blood samples were collected (14–18, 24–26, 30–32, 34–36, and 38–40 weeks), stored at −80°C, and evaluated for serum levels ...
Nilson R. de Jesús+7 more
wiley +1 more source
Genetic diversity and verification of plant material compliance of Cocoa (Theobroma cacao L.) in the Barombi-Kang Regional variety trial. [PDF]
Eyango NMC+6 more
europepmc +1 more source
Metabolic Consequences of Rheumatoid Arthritis
Patients with rheumatoid arthritis (RA) may have metabolic disruption, which can contribute to adverse long‐term outcomes, for multiple reasons. Patients with RA appear to have a higher risk of sarcopenia, type 1 and type 2 diabetes mellitus, metabolic syndrome, and hypertension. Systemic inflammation in RA can cause a “lipid paradox,” with reduced low‐
Stevie Barry+2 more
wiley +1 more source