Results 91 to 100 of about 1,286,422 (323)
Exploring lipid diversity and minimalism to define membrane requirements for synthetic cells
Designing the lipid membrane of synthetic cells is a complex task, in which its various roles (among them solute transport, membrane protein support, and self‐replication) should all be integrated. In this review, we report the latest top‐down and bottom‐up advances and discuss compatibility and complexity issues of current engineering approaches ...
Sergiy Gan +2 more
wiley +1 more source
A Comparison of Void-finding Algorithms Using Crossing Numbers
We study how well void-finding algorithms identify cosmic void regions and whether we can quantitatively and qualitatively compare the voids they find with dynamical information from the underlying matter distribution.
Dahlia Veyrat +2 more
doaj +1 more source
Coherent band pathways between knots and links
We categorise coherent band (aka nullification) pathways between knots and 2-component links. Additionally, we characterise the minimal coherent band pathways (with intermediates) between any two knots or 2-component links with small crossing number.
Buck, Dorothy, Ishihara, Kai
core +1 more source
Spinal muscular atrophy (SMA) is a genetic disease affecting motor neurons. Individuals with SMA experience mitochondrial dysfunction and oxidative stress. The aim of the study was to investigate the effect of an antioxidant and neuroprotective substance, ergothioneine (ERGO), on an SMNΔ7 mouse model of SMA.
Francesca Cadile +8 more
wiley +1 more source
The warping degree of a link diagram [PDF]
For an oriented link diagram D, the warping degree d(D) is the smallest number of crossing changes which are needed to obtain a monotone diagram from D. We show that d(D)+d(-D)+sr(D) is less than or equal to the crossing number of D, where -D denotes the
Shimizu, Ayaka
core
Approximating the rectilinear crossing number
A straight-line drawing of a graph $G$ is a mapping which assigns to each vertex a point in the plane and to each edge a straight-line segment connecting the corresponding two points. The rectilinear crossing number of a graph $G$, $\overline{cr}(G)$, is the minimum number of crossing edges in any straight-line drawing of $G$. Determining or estimating
Fox, Jacob, Pach, János, Suk, Andrew
openaire +5 more sources
Microbial exopolysaccharide production by polyextremophiles in the adaptation to multiple extremes
Polyextremophiles are microorganisms that endure multiple extreme conditions by various adaptation strategies that also include the production of exopolysaccharides (EPSs). This review provides an integrated perspective on EPS biosynthesis, function, and regulation in these organisms, emphasizing their critical role in survival and highlighting their ...
Tracey M Gloster, Ebru Toksoy Öner
wiley +1 more source
Crossing number of Cartesian product of prism and path
An m-prism is the Cartesian product of an m-cycle and a path with 2 vertices. We prove that the crossing number of the join of an m-prism () and a graph with k isolated vertices is km for each We then use this result to prove that the crossing number of ...
Yip C. Yiew, Gek L. Chia, Poh-Hwa Ong
doaj +1 more source
Antimicrobial resistance (AMR) is of huge importance, resulting in over 1 million deaths each year. Here, we describe how a new drug, enmetazobactam, designed to help fight resistant bacterial diseases, inhibits a key enzyme (GES‐1) responsible for AMR. Our data show it is a more potent inhibitor than the related tazobactam, with high‐level computation
Michael Beer +10 more
wiley +1 more source
Mutations in the C9orf72 gene represent the most common genetic cause of amyotrophic lateral sclerosis (ALS), a fatal neurodegenerative disease. Using patient‐derived neurons and C. elegans models, we find that the nucleoporin Nup107 is dysregulated in C9orf72‐associated ALS. Conversely, reducing Nup107 levels mitigates disease‐related changes.
Saygın Bilican +7 more
wiley +1 more source

