Results 111 to 120 of about 11,183,836 (302)
Barekeng, 2019 Forecasting the number of passengers can be a consideration for managers of Gorontalo Crossing Port regarding the provision of tickets. The number of passengers can be influenced by certain seasonal or special events.
Muhammad Rezky Friesta Payu, N. Nurwan
doaj +1 more source
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
Molecular Oncology, EarlyView.We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
A Karnaugh-Map based fingerprint minutiae extraction method [PDF]
Songklanakarin Journal of Science and Technology (SJST), 2010 Fingerprint is one of the most promising method among all the biometric techniques and has been used for thepersonal authentication for a long time because of its wide acceptance and reliability.
Sunil Kumar Singla, Ajat Shatru Arora
doaj
Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition
Molecular Oncology, EarlyView.We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li +10 more
wiley +1 more source
Study of Drivers’ Behaviour at a Passive Railway Crossing
Promet (Zagreb), 2012 Problem: The number of killed and injured persons in incidents at railway level crossings is generally increasing on the Serbian Railways, particularly at passive crossings. In this paper we researched the direct behaviour of road traffic participants at
Sandra Kasalica +2 more
doaj +1 more source
Molecular Oncology, EarlyView.This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source
From the Crossing Numbers of K5 + Pn and K5 + Cn to the Crossing Numbers of Wm + Sn and Wm + Wn
AxiomsThe crossing number of a graph is a significant measure that indicates the complexity of the graph and the difficulty of visualizing it. In this paper, we examine the crossing numbers of join products involving the complete graph K5 with discrete graphs,
Michal Staš +2 more
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, 2009 Das Kreuzungszahlproblem wird von Graphentheoretikern seit über 60 Jahren betrachtet, jedoch ist noch immer sehr wenig über dieses einfache und zugleich hochkomplizierte Ma der Nichtplanarität bekannt. Die Aufgabenstellung ist simpel: Gegeben ein Graph, zeichnen Sie ihn mit der kleinstmöglichen Anzahl an Kantenkreuzungen.
openaire +2 more sources
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source