Results 121 to 130 of about 9,538,132 (298)

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

On the 2-Colored Crossing Number

open access: yes, 2019
Let $D$ be a straight-line drawing of a graph. The rectilinear 2-colored crossing number of $D$ is the minimum number of crossings between edges of the same color, taken over all possible 2-colorings of the edges of $D$. First, we show lower and upper bounds on the rectilinear 2-colored crossing number for the complete graph $K_n$.
Oswin Aichholzer   +6 more
openaire   +3 more sources

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

The crossing number of K1,4,n

open access: yes, 2007
In this paper, we prove that the crossing number of the complete tripartite graph K1,4,n is n(n-1). Our result also shows that the crossing number of the Cartesian product S4□Sn is n(n-1), where Sn denotes the star K1,n for arbitrary integer n ...
Yuanqiu Huang   +3 more
core   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

General lower bounds for the minor crossing number of graphs

open access: yes, 2015
There are three general lower bound techniques for the crossing numbers of graphs: the Crossing Lemma, the bisection method and the embedding method. Inthis contribution, we present their adaptations to the minor crossing number. Using the adapted bounds,
Vrt\u27o, Imrich   +3 more
core  

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

CONSTRUCTION OF INFINITE FAMILIES OF ALMOST PLANAR GRAPH WITH GIVEN CROSSING NUMBER [PDF]

open access: yes, 2020
A graph is a pair of a non-empty set of vertices and a set of edges. Graphs can be drawn on the plane with or without crossing of its edges. Crossing number of a graph is the minimal number of crossings among all drawings of the graph on the plane ...
Benny Pinontoan
core  

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