Results 121 to 130 of about 10,813,555 (336)

Circulating tumor DNA (ctDNA) trajectories predict survival in trifluridine/tipiracil‐treated metastatic colorectal cancer patients

open access: yesMolecular Oncology, EarlyView.
The authors applied joint/mixed models that predict mortality of trifluridine/tipiracil‐treated metastatic colorectal cancer patients based on circulating tumor DNA (ctDNA) trajectories. Patients at high risk of death could be spared aggressive therapy with the prospect of a higher quality of life in their remaining lifetime, whereas patients with a ...
Matthias Unseld   +7 more
wiley   +1 more source

The rectilinear local crossing number of $K_n$

open access: yes, 2017
We determine ${\bar{\rm{lcr}}}(K_n)$, the rectilinear local crossing number of the complete graph $K_n$ for every $n$. More precisely, for every $n \notin \{8, 14 \}, $ \[ {\bar{\rm{lcr}}}(K_n)=\left\lceil \frac{1}{2} \left( n-3-\left\lceil \frac{n-3}{3}
Fernández-Merchant, Silvia   +1 more
core  

Peripheral blood proteome biomarkers distinguish immunosuppressive features of cancer progression

open access: yesMolecular Oncology, EarlyView.
Immune status significantly influences cancer progression. This study used plasma proteomics to analyze benign 67NR and malignant 4T1 breast tumor models at early and late tumor stages. Immune‐related proteins–osteopontin (Spp1), lactotransferrin (Ltf), calreticulin (Calr) and peroxiredoxin 2 (Prdx2)–were associated with systemic myeloid‐derived ...
Yeon Ji Park   +6 more
wiley   +1 more source

Marking Algorithms in Permutation Tableaux and Transformations on Linked Partitions

open access: yesMathematics
In this paper, we focus on the internal structural characteristics of permutation tableaux and their correspondence with linked partitions. We begin by introducing new statistics for permutation tableaux, designed to thoroughly describe various ...
Carol Jian Wang, Meryl Nan Wang
doaj   +1 more source

Various heuristic algorithms to minimise the two-page crossing numbers of graphs

open access: yesOpen Computer Science, 2015
We propose several new heuristics for the twopage book crossing problem, which are based on recent algorithms for the corresponding one-page problem. Especially, the neural network model for edge allocation is combined for the first time with various one-
He Hongmei   +3 more
doaj   +1 more source

Adverse prognosis gene expression patterns in metastatic castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
We aggregated a cohort of 1012 mCRPC tissue samples from 769 patients and investigated the association of gene expression‐based pathways with clinical outcomes. Loss of AR signaling, high proliferation, and a glycolytic phenotype were independently prognostic for poor outcomes, and an adverse transcriptional feature score incorporating these pathways ...
Marina N. Sharifi   +26 more
wiley   +1 more source

The genus crossing number [PDF]

open access: yesArs Mathematica Contemporanea, 2009
Pach and Toth [PT] introduced a new version of the crossing number parameter, called the degenerate crossing number, by considering proper drawings of a graph in the plane and counting multiple crossing of edges through the same point as a single crossing when all pairwise crossings of edges at that point are transversal. We propose a related parameter,
openaire   +2 more sources

TOMM20 as a driver of cancer aggressiveness via oxidative phosphorylation, maintenance of a reduced state, and resistance to apoptosis

open access: yesMolecular Oncology, EarlyView.
TOMM20 increases cancer aggressiveness by maintaining a reduced state with increased NADH and NADPH levels, oxidative phosphorylation (OXPHOS), and apoptosis resistance while reducing reactive oxygen species (ROS) levels. Conversely, CRISPR‐Cas9 knockdown of TOMM20 alters these cancer‐aggressive traits.
Ranakul Islam   +9 more
wiley   +1 more source

The Zero Divisor Graph of the Ring Zqp.

open access: yesScience Journal of University of Zakho, 2015
In this paper we construct a star zero divisor graph from the zero divisor graph of the ring Zqp. The star zero divisor graph is obtained by removing some vertices from the zero divisor graph Γ(Zqp), in different ways , but the best way to get star zero ...
Nazar H. Shuker, Payman A. Rashed
doaj  

Bound for the 2-Page Fixed Linear Crossing Number of Hypercube Graph via SDP Relaxation

open access: yesJournal of Applied Mathematics, 2017
The crossing number of graph G is the minimum number of edges crossing in any drawing of G in a plane. In this paper we describe a method of finding the bound of 2-page fixed linear crossing number of G. We consider a conflict graph G′ of G.
A. Suebsriwichai, T. Mouktonglang
doaj   +1 more source

Home - About - Disclaimer - Privacy