Results 121 to 130 of about 624,423 (312)

Crossing Over…Markov Meets Mendel

PLoS Comput. Biol., 2012
Chromosomal crossover is a biological mechanism to combine parental traits. It is perhaps the first mechanism ever taught in any introductory biology class.
S. Mneimneh
semanticscholar   +1 more source

Developing know-how for the improvement and sustainable management of teak genetic resources [PDF]

, 2008
The project had the following objectives: To trace and quantify genetic diversity of teak within its natural range, DNA markers were used to assay the current distribution of genetic diversity within and between populations, investigate its mating ...
Cavers, Stephen, Davies, Samantha, Lowe, Andrew, Puthanveettil, Indira, Sudarsono, S., Van Der Straeten, Dominique, Vanavichit, Apichart, Volkaert, Hugo, Wellendorf, Hubert   +8 more
core  

Rad51/Dmc1 paralogs and mediators oppose DNA helicases to limit hybrid DNA formation and promote crossovers during meiotic recombination [PDF]

, 2014
This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original ...
Lorenz, Alexander, Mehats, Alizée, Osman, Fekret, Whitby, Matthew C   +3 more
core   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Optimization Iteration Min-Max Cross Over Genetic Algorithm To Generate Fuzzy membership Function Automatically

Journal of Physics: Conference Series, 2019
Abstract Generating membership function fuzzy for Fuzzy system is important to representative of the problem. Some research generating a membership function automatic had done and still have a problem to generate procces in max iterasi, so that this research will generating membership function fuzzy otomatic used genetic algorithm by ...
E S Barus, Niskarto Zendrato, Diana Alemin Barus, Pilipus Tarigan, Khairuman Khairuman, Andi Elhanafi, Jenni Veronika Ginting, Hasanul Fahmi   +7 more
openaire   +1 more source

DNA repair and crossing over favor similar chromosome regions as discovered in radiation hybrid of Triticum

BMC Genomics, 2012
BackgroundThe uneven distribution of recombination across the length of chromosomes results in inaccurate estimates of genetic to physical distances. In wheat (Triticum aestivum L.) chromosome 3B, it has been estimated that 90% of the cross over events ...
Ajay Kumar, F. Bassi, E. Paux, O. Al-Azzam, Monika Michalak de Jiménez, A. Denton, Y. Gu, E. Huttner, A. Kilian, Sachin Kumar, A. Goyal, M. Iqbal, V. Tiwari, M. Doğramacı, H. Balyan, H. Dhaliwal, P. Gupta, G. S. Randhawa, C. Feuillet, W. Pawlowski, S. Kianian   +20 more
semanticscholar   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Genetic Variation in a Crossing Population of Camellia oleifera Based on ddRAD Sequencing and Analysis of Association with Fruit Traits

Current Issues in Molecular Biology
Tea oil is an important high-quality edible oil derived from woody plants. Camellia oleifera is the largest and most widely planted oil-producing plant in the Camellia genus in China, and its seeds are the most important source for obtaining tea oil.
Lexin Zhou, Yu Li, Ling Ye, Jiani Li, Tian Liang, Yanxuan Liu, Weiwei Xie, Yiqing Xie, Shipin Chen, Hui Chen   +9 more
doaj   +1 more source

Patterns of Inter-Chromosomal Gene Conversion on the Male-Specific Region of the Human Y Chromosome [PDF]

, 2017
The male-specific region of the human Y chromosome (MSY) is characterized by the lack of meiotic recombination and it has long been considered an evolutionary independent region of the human genome.
Cruciani, Fulvio, D'Atanasio, Eugenia, Trombetta, Beniamino   +2 more
core   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source