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Considerations for crossover design in clinical study [PDF]

open access: yesKorean Journal of Anesthesiology, 2021
This article introduces a crossover design that is often used in clinical studies, with the advantage of comparing treatment effects within one study subject. In particular, the advantages and disadvantages of the two-period, two-sequence crossover design (2 × 2 or AB/BA crossover design), which is widely used in clinical practice, are identified, and
Chi-Yeon Lim, Junyong In
openaire   +3 more sources

The use of baseline covariates in crossover studies [PDF]

open access: yesBiostatistics, 2009
It is our experience that in many settings, crossover trials that have within-period baseline measurements are analyzed wrongly. A "conventional" analysis of covariance in this setting uses each baseline as a covariate for the following outcome variable in the same period but not for any other outcome.
Kenward, Michael G., Roger, James H.
openaire   +3 more sources

A crossover study of short daily haemodialysis [PDF]

open access: yesNephrology Dialysis Transplantation, 2005
The benefits of daily haemodialysis (DHD) compared to conventional three times per week haemodialysis (CHD) have been described in a number of observational studies. Most of these previous studies however have not been performed with rigorous controls.We performed a crossover study following an A-B-A design: phase A was 4 weeks of thrice weekly ...
Alexander S, Goldfarb-Rumyantzev   +4 more
openaire   +2 more sources

A μSR study of the spin-crossover

open access: yesJournal of Physics and Chemistry of Solids, 2004
The spin-crossover phenomenon is a cooperative low-spin to high-spin transition which can be initiated using temperature or light-irradiation. We have used muon-spin relaxation (μSR) to study this effect in Fe(PM-PEA)2(NCS)2 and Fe(PMAzA)2(NCS)2. We find Gaussian or exponential muon relaxation in the high-spin phase for the two compounds, reflecting ...
Blundell, S   +4 more
openaire   +4 more sources

Nonparametric Approaches to the Analysis of Crossover Studies

open access: yesStatistical Science, 2004
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Putt, Mary E., Chinchilli, Vernon M.
openaire   +3 more sources

Sample size estimation for case‐crossover studies

open access: yesStatistics in Medicine, 2018
Case‐crossover study designs are observational studies used to assess postmarket safety of medical products (eg, vaccines or drugs). As a case‐crossover study is self‐controlled, its advantages include better control for confounding because the design controls for any time‐invariant measured and unmeasured confounding and potentially greater ...
Sai Dharmarajan   +2 more
openaire   +4 more sources

crossover study

open access: yes
Citation: 'crossover study' in the IUPAC Compendium of Chemical Terminology, 5th ed.; International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.15165 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms.
openaire   +1 more source

Case-Crossover Study

open access: yesJapanese Journal of Pharmacoepidemiology/Yakuzai ekigaku, 2014
SHIOSAKAI, Kazuhito, KAGIMURA, Tatsuo
openaire   +2 more sources

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