Antibacterial and Hemolytic Activity of Crotalus triseriatus and Crotalus ravus Venom [PDF]
Animals, 2020 Rattlesnakes have venoms with a complex toxin mixture comprised of polypeptides and proteins. Previous studies have shown that some of these polypeptides are of high value for the development of new medical treatments.
Adrian Zaragoza-Bastida +8 more
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Phenotypic dichotomy in Crotalus durissus ruruima venom and potential consequences for clinical management of snakebite envenomations. [PDF]
PLoS Neglected Tropical DiseasesBackgroundPhenotypic polymorphism in rattlesnake venoms is well-documented, with a dichotomy between hemorrhagic (Type I) and neurotoxic (Type II) venoms.
Mônica Colombini +15 more
doaj +2 more sources
Crotoxin B from the South American Rattlesnake Crotalus vegrandis Blocks Voltage-Gated Calcium Channels Independent of Its Intrinsic Catalytic Activity [PDF]
ToxinsNeurotoxicity following South American Crotalus rattlesnake bite is primarily caused by crotoxin, the most abundant component in their venom. Despite the central role of voltage-gated calcium channels (CaV) in neurotransmission, direct targetability by ...
Markus Eicheldinger +5 more
doaj +2 more sources
Local and systemic effects caused by Crotalus durissus terrificus, Crotalus durissus collilineatus, and Crotalus durissus cascavella snake venoms in swiss mice [PDF]
Revista da Sociedade Brasileira de Medicina Tropical, 2019 INTRODUCTION: Crotalus envenomations cause serious complications and can be fatal without appropriate treatment. Venom isoforms present and inter/intraspecific variations in the venom composition can result in different symptoms presented by bites by ...
Letícia Helena de Carvalho +13 more
doaj +6 more sources
Bioprospection of rattlesnake venom peptide fractions with anti-adipose and anti-insulin resistance activity in vitro [PDF]
Toxicon: XAnimal venoms are natural products that have served as a source of novel molecules that have inspired novel drugs for several diseases, including for metabolic diseases such as type-2 diabetes and obesity. From venoms, toxins such as exendin-4 (Heloderma
David Meléndez-Martínez +12 more
doaj +2 more sources
Caracterización clínica del paciente pediátrico atendido por mordedura de serpiente, Hospital Escuela, Tegucigalpa, 2015-2019 [PDF]
Revista Médica Hondureña, 2021 Antecedentes: Las manifestaciones clínicas de las mordeduras de serpientes son similares en adultos y niños, aunque más graves en estos últimos debido a la proporción de veneno inoculado por la serpiente y el tamaño corporal del paciente pediátrico ...
Scheybi Teresa Miralda Méndez
doaj +1 more source
A novel activity on thymocytes cells exerted by the rattlesnake (Crotalus durissus cumanensis) venom
Biomédica: revista del Instituto Nacional de Salud, 2021 Introduction: The thymus is active mainly during the neonatal and pre-adolescent periods. Objective: To test naïve thymocytes proliferation and monocytes stimulation. Materials and methods: We collected fresh thymus tissue from neonate mice after surgery.
María M. Pulido-Méndez +2 more
doaj +1 more source
Crotalic accidents in Brazil: actualities and perspectives
Revista Médica de Minas Gerais, 2022 Introduction: Ophidian accidents are neglected events in tropical and in developing countries, including Brazil. Serpents of the Crotalus genus (rattlesnakes) are those that produce the highest case-fatality in the country.
Hammer, Fernanda Martins +2 more
doaj +1 more source
Repurposing cancer drugs, batimastat and marimastat, to inhibit the activity of a group I metalloprotease from the venom of the Western Diamondback rattlesnake, Crotalus atrox [PDF]
, 2020 Snakebite envenomation causes over 140,000 deaths every year predominantly in developing countries. As a result, it is one of the most lethal neglected tropical diseases.
Bicknell, Andrew B. +12 more
core +1 more source
Tetrodotoxin-insensitive electrical field stimulation-induced contractions on Crotalus durissus terrificus corpus cavernosum. [PDF]
PLoS ONE, 2017 Reptiles are the first amniotes to develop an intromitent penis, however until now the mechanisms involved in the electrical field stimulation-induced contraction on corpora cavernosa isolated from Crotalus durissus terrificus were not investigated ...
Rafael Campos +8 more
doaj +1 more source