Results 131 to 140 of about 4,036,534 (282)
Advanced Science, EarlyView.The effect of ligand reactivity and carrier mechanics on thiol‐mediated uptake was investigated at the single‐molecule/particle level. The interaction kinetics of LA and AspA with membrane thiols were quantified; AspA is more efficient due to the higher binding affinity, greater binding stability, and more double‐disulfide binding, as well as greater ...
Zhuang Zhang +7 more
wiley +1 more source
Parametric Conditional Monte Carlo Density Estimation [PDF]
In applied density estimation problems, one often has data not only on the target variable, but also on a collection of covariates. In this paper, we study a density estimator that incorporates this additional information by combining parametric ...
John Stachurski, Yin Liao
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Advanced Science, EarlyView.Mechanical orthodontic treatment for malocclusion is limited by slow remodeling and risks due to poor biomechanical sensing. This study shows that static magnetic fields (SMFs) enhance mechanical sensation in periodontal ligament cells, promoting inflammation and osteoclast activity.
Yiling Lou +11 more
wiley +1 more source
Nonparametric Estimation and Symmetry Tests for Conditional Density Functions. [PDF]
We suggest two new methods for conditional density estimation. The first is based on locally fitting a log-linear model, and is in the spirit of recent work on locally parametric techniques in density estimation.
Hyndman, R.J., Yao, Q.
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Advanced Science, EarlyView.By merging centrifugal microfluidics, precise temperature control, and AI image recognition, T‐PhaseMap transforms biomolecular condensate phase mapping into a rapid, temperature‐resolved workflow. It generates 3D composition–temperature phase diagrams within 30 min, resolves four phase states, and uncovers temperature‐dependent heparin sodium ...
Jiashuo Li +6 more
wiley +1 more source
Advanced Science, EarlyView.Mesenchymal GSCs preferentially uptake palmitic acid, thereby promoting ZDHHC12‐mediated LDHA palmitoylation. This modification enhances LDHA enzymatic activity, drives glycolytic reprogramming, and facilitates exosomal LDHA‐mediated TAM regulation.
Zijie Gao +20 more
wiley +1 more source
Seeing the Chemistry of Biomolecular Condensates: In Situ Mapping of Composition and Water Content
Advanced Science, EarlyView.Raman hyperspectral imaging combined with spectral phasor analysis enables a label‐free quantification of proteins, polymers and water density within individual biomolecular condensates. By transforming complex vibrational fingerprints into intuitive compositional maps, the approach reveals the high water content and structural heterogeneity of ...
E. Sabri +3 more
wiley +1 more source
Anode‐Free Sodium Metal Batteries: From Materials Design to System‐Level Integration
Advanced Science, EarlyView.Anode‐free sodium metal batteries hold no sodium reserve, so every inefficiency becomes permanent loss. Resolving the inventory into reversible, dead, and chemically bound fractions exposes what Coulombic efficiency hides. Practical 500‐cycle operation requires above 99.95%, a threshold few systems meet under lean electrolyte and high areal capacity ...
Hamid Hussain +10 more
wiley +1 more source
Advanced Science, EarlyView.DAIMS is a multimodal model for treatment stratified risk and survival assessment in colorectal cancer. Training draws on pathology, genomics, and clinical reports, yet inference requires only whole slide images, and adaptation to new cohorts proceeds without target survival outcomes.
Chuangjie Cao +15 more
wiley +1 more source
Crowd density estimation in extremely crowded images
, 2015 In a variety of situations that involve a large number of people, there have always been huge difficulties in identifying an estimation of the number of people involved for the purpose of crowd management and the like.
Garcia, John Paul +2 more
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