Results 161 to 170 of about 595,828 (287)

Over‐the‐Top Anterior Cruciate Ligament Reconstruction With Lateral Extra‐articular Tenodesis in Pediatric Athletes Provides Excellent Functional Outcomes and Preserves Growth Plate Symmetry

Arthroscopy, Sports Medicine, and Rehabilitation, EarlyView.
Purpose To assess clinical and radiological outcomes of pediatric anterior cruciate ligament (ACL) reconstruction using the over‐the‐top technique (OTT) combined with the lateral extra‐articular tenodesis (LET) technique in skeletally immature patients, providing insights into its safety, efficacy, and effects on the growing knee.
Abel Gomez‐Caceres, Ivan Medina‐Porqueres, Manuel Benavides Propp, Almudena Perez Lara, Ignacio Vieitez‐Riestra, Raphael Pierre Idiart‐Charrier, Iskandar Tamimi‐Mariño   +6 more
wiley   +1 more source

C-Reactive Protein Trajectories by Summary Metric Across the Coronavirus-2019 Period: A 16-Year Interrupted Time-Series Analysis (2008-2023). [PDF]

Diagnostics (Basel)
Han JS, Jung BK, Jeon JS, Kim JK.
europepmc   +1 more source

Cytokine Pathways Driving Diverse Tissue Pathologies in Rheumatoid Arthritis

Arthritis &Rheumatology, EarlyView.
Rheumatoid arthritis (RA) is a complex systemic disorder characterized primarily by articular inflammation and destruction with associated functional loss and reduced quality of life. RA is also associated with extra‐articular disease, such as that of the lung, with potentially devastating clinical consequences. The critical importance of comorbidities,
Aurelie Najm, Lyn D. Ferguson, Iain B. McInnes   +2 more
wiley   +1 more source

Plasma Proteomics Identifies Thousand‐and‐One–Amino Acid Kinase 3 as a Potential Biomarker of Rheumatoid Arthritis Activity and a Novel Therapeutic Target

Arthritis &Rheumatology, EarlyView.
Objective Bone destruction associated with active rheumatoid arthritis (RA) remains a major therapeutic challenge, with a lack of reliable molecular markers reflecting bone injury. This study aims to identify novel biomarkers linked to bone destruction in active RA through proteomic analysis, providing new strategies for precise monitoring and targeted
Pengfei Xin, Wenzhen Li, Xinyu A, Jun Shen, Xiaohui Meng, Yanqin Bian, Haihui Han, Zheng Xiang, Lei Ran, Songtao Sun, Jun Xie, Tao Yue, Qi Zhu, Xiaoming Zhang, Lu Xie, Lianbo Xiao   +15 more
wiley   +1 more source

Combining CRP testing and patient information leaflets to safely reduce antibiotic use for acute respiratory tract infections in adults: Protocol for the 2CARE randomised controlled trial in Kyrgyz primary care. [PDF]

PLoS One
Akylbekov A, Isaeva E, Mademilov M, Siersma V, Risør T, Arnold SH, Kjærgaard J, Sreenivasan N, Zaman AW, Sooronbaev T, Aabenhus RM.   +10 more
europepmc   +1 more source

Molecular Stratification of Antiphospholipid Syndrome Through Integrative Analysis of the Whole‐Blood RNA Transcriptome

Arthritis &Rheumatology, EarlyView.
Objective Antiphospholipid syndrome (APS) is a thromboinflammatory disorder characterized by clinical and mechanistic heterogeneity that complicates early diagnosis and hinders targeted treatment. We aimed to identify distinct molecular endotypes among antiphospholipid antibody (aPL)–positive patients using whole‐blood transcriptomics.
Amala Ambati, Feiyang Ma, Katarina Kmetova, Sherwin Navaz, Claire K. Hoy, Cyrus Sarosh, Ajay Tambralli, Erika Navarro‐Mendoza, Johann E. Gudjonsson, J. Michelle Kahlenberg, Jacqueline A. Madison, Alí Duarte‐García, Jason S. Knight, Yu Zuo   +13 more
wiley   +1 more source

Is three-phase bone scintigraphy really obsolete? : a combined TPBS-CRP diagnostic method. [PDF]

Bone Joint Res
Chen Q, Li Y, Guo X, Wlamu W, Mu W, Ji B, Cao L, Zhang X.   +7 more
europepmc   +1 more source

Interleukin‐18 Levels Are Associated With Disease Course in Patients With Still Disease Treated With Interleukin‐1 Inhibitors

Arthritis &Rheumatology, EarlyView.
Objective To evaluate the prognostic utility of circulating interleukin‐18 (IL‐18) levels in predicting disease activity, macrophage activation syndrome (MAS), and disease course in patients with Still disease (SD) receiving first‐line IL‐1 inhibitors (IL‐1i).
Matteo Trevisan, Manuela Pardeo, Ivan Caiello, Claudia Bracaglia, Arianna De Matteis, Valentina Matteo, Elena Loricchio, Fabrizio De Benedetti, Giusi Prencipe   +8 more
wiley   +1 more source

Dose-Response Association Between Handgrip Strength and All-Cause Mortality Across Different Levels of Systemic Inflammation. [PDF]

J Cachexia Sarcopenia Muscle
Tur-Boned A, Andersen LL, López-Bueno R, Núñez-Cortés R, Cruz-Montecinos C, Suso-Martí L, Polo-López A, Calatayud J.   +7 more
europepmc   +1 more source

Dual Action of Dipyridamole in Experimental Rheumatoid Arthritis: Suppression of Joint Inflammation and Upregulation of Muscle Anabolism via Adenosine and AMPK Pathways

Arthritis &Rheumatology, EarlyView.
Objective Rheumatoid sarcopenia, characterized by the progressive loss of skeletal muscle mass and function, is a frequent comorbidity in rheumatoid arthritis (RA), linked to prolonged, severe systemic inflammation. Purinergic signaling (adenosine, AMP, and ATP) plays a crucial role in inflammation, myogenesis, and muscle hypertrophy.
Miguel Marco‐Bonilla, Maria Fresnadillo, Irene Sanchez‐Platero, Macarena de la Riva‐Bueno, Fernando Huete‐Toral, Gonzalo Carracedo, Carmen Conde, Yolanda Benitez, Pablo Minguez, Sandra Carolina Cifuentes, Joaquin Rams, Gabriel Herrero‐Beaumont, Raquel Largo, Aránzazu Mediero   +13 more
wiley   +1 more source