Results 1 to 10 of about 12,518 (182)

Midazolam Dosing During CRRT: A Combined Ex Vivo and Physiologically-Based Pharmacokinetic Approach. [PDF]

CPT Pharmacometrics Syst Pharmacol
ABSTRACT Children supported with continuous renal replacement therapy have high mortality rates ranging from 30% to 70%. The cause of this high mortality is multifactorial and includes ineffective drug dosing and altered drug pharmacokinetics. Changes in drug exposure can result from (1) underlying disease; and (2) direct drug interaction and/or ...
McKnite AM, Hamadeh A, Hunt JP, Green DJ, Imburgia C, Whelan A, Hudson R, Chevalier A, Mathis CL, Yang MJ, Dwyer JP, Edginton A, Watt KM.   +12 more
europepmc   +2 more sources

Continuous renal replacement therapy attenuates endothelial injury biomarkers in pediatric sepsis: a prospective cohort study [PDF]

Renal Failure
Endothelial cell (EC) injury is a critical factor in sepsis-induced organ failure. Continuous renal replacement therapy (CRRT) is used to improve hemodynamically unstable sepsis.
Huijie Miao, Chunxia Wang, Yun Cui, Xi Xiong, Yuqian Ren, Zhibao Lv, Yucai Zhang   +6 more
doaj   +2 more sources

Risk Factors Associated with 30-day Mortality in Patients with Postoperative Acute Kidney Injury Who Underwent Continuous Renal Replacement Therapy in the Intensive Care Unit [PDF]

Journal of Acute Care Surgery, 2022
Purpose To evaluate the risk factors associated with 30-day mortality in patients with postoperative acute kidney injury who underwent continuous renal replacement therapy (CRRT).
Kang Yoon Lee, Kwanhoon Park, SungHo Lee, Ji Young Jang, Keum Seok Bae   +4 more
doaj   +1 more source

Comparison of the Effects of Continuous Renal Replacement Therapy and Hemodialysis on Complications, Vital Signs, and Laboratory Parameters in Patients with COVID-19

Mediterranean Journal of Infection, Microbes and Antimicrobials, 2022
Introduction: Evidence shows that continuous renal replacement therapy (CRRT) and hemodialysis may be effective in the treatment of Coronavirus disease-2019 (COVID-19).
Shahrzad IZADI, Mohammad MEMARIAN, Zahra Shaabani KHATIB, Samaneh LAVAF, Kamyar MANSORI   +4 more
doaj   +1 more source

The landscape of renal replacement therapy in Veterans Affairs Medical Center intensive care units

Renal Failure, 2021
Background Outpatient dialysis is standardized with several evidence-based measures of adequacy and quality that providers aim to meet while providing treatment.
Chandan Vangala, Maulin Shah, Natasha N. Dave, Layth Al Attar, Sankar D. Navaneethan, Venkat Ramanathan, Susan Crowley, Wolfgang C. Winkelmayer   +7 more
doaj   +1 more source

Continuous renal replacement therapy attenuates polymorphonuclear myeloid-derived suppressor cell expansion in pediatric severe sepsis

Frontiers in Immunology, 2022
BackgroundMyeloid-derived suppressor cells (MDSCs) expansion is an important mechanism underlying immunosuppression during sepsis. Though continuous renal replacement therapy (CRRT) may attenuate hyperinflammatory response in sepsis, its role in ...
Shuyun Feng, Shuyun Feng, Yun Cui, Yun Cui, Yun Cui, Yiping Zhou, Yiping Zhou, Yiping Zhou, Lujing Shao, Lujing Shao, Huijie Miao, Huijie Miao, Jiaying Dou, Jiaying Dou, Jiaying Dou, Tiantian Liu, Tiantian Liu, Chunxia Wang, Chunxia Wang, Chunxia Wang, Chunxia Wang, Yucai Zhang, Yucai Zhang, Yucai Zhang   +23 more
doaj   +1 more source

Association of Serum Phosphate Derangement With Mortality in Patients on Continuous Renal Replacement Therapy

Canadian Journal of Kidney Health and Disease, 2022
Background: There is limited evidence on the association of serum phosphate with mortality in patients receiving continuous renal replacement therapy (CRRT).
Charat Thongprayoon, Yeshwanter Radhakrishnan, Wisit Cheungpasitporn, Tananchai Petnak, Fawad Qureshi, Michael A. Mao, Kianoush B. Kashani   +6 more
doaj   +1 more source

Economic Analysis of Renal Replacement Therapy Modality in Acute Kidney Injury Patients With Fluid Overload

Critical Care Explorations, 2023
OBJECTIVES:. Acute kidney injury (AKI) and fluid overload (FO) are among the top reasons to initiate intermittent hemodialysis (IHD) or continuous renal replacement therapy (CRRT).
Olivier Ethgen, PhD, Raghavan Murugan, MD, MS, FRCP, Jorge Echeverri, MD, Michael Blackowicz, PhD, Kai Harenski, MD, Marlies Ostermann, PhD   +5 more
doaj   +1 more source

Predictors for short-term successful weaning from continuous renal replacement therapy: a systematic review and meta-analysis

Renal Failure, 2023
The systemic review and meta-analysis aimed to identify the predictors for short-term successful weaning from CRRT in severe AKI patients. PubMed, Embase, the Cochrane Library, and grey literature were searched for relevant studies investigating ...
Yu Li, Xiaoqi Deng, Jiaxing Feng, Bo Xu, Yulei Chen, Zhanying Li, Xiaodan Guo, Tianjun Guan   +7 more
doaj   +1 more source

Earlier continuous renal replacement therapy is associated with reduced mortality in rhabdomyolysis patients

Renal Failure, 2022
Background Continuous renal replacement therapy (CRRT) is commonly employed for rhabdomyolysis (RM) patients. However, the optimal initiation timing of CRRT and prognostic factors were not well evaluated for patients with RM.
Xiayin Li, Ming Bai, Yan Yu, Feng Ma, Lijuan Zhao, Yajuan Li, Hao Wu, Lei Zhou, Shiren Sun   +8 more
doaj   +1 more source