Results 31 to 40 of about 12,518 (182)

Therapeutic drug monitoring of antimicrobials in a paediatric setting: A retrospective single‐centre study

British Journal of Clinical Pharmacology, EarlyView.
Aims Paediatric pharmacokinetics differ significantly from adults due to age‐related physiological changes, necessitating precise dose adjustments. However, data on therapeutic drug monitoring (TDM) implementation in paediatric setting remain limited.
Gianluca Gazzaniga, Stefano Agliardi, Riccardo Giossi, Alice Schianchi, Alessandra Romandini, Thomas Virdis, Silvia Nerini Molteni, Maria Luisa De Angelis, Stefania Paccagnini, Cecilia Gechtman, Alice Proto, Marco Fossati, Silvia Oliveri, Giulia Angela Pattarino, Elena Altieri, Agnese Graziosi, Arianna Pani, Romano Danesi, Stefano Martinelli, Costantino De Giacomo, Francesco Scaglione   +20 more
wiley   +1 more source

Influence of patient factors on target plasma volume treated attainment rate during double filtration plasmapheresis in patients with hypertriglyceridemic acute pancreatitis

Therapeutic Apheresis and Dialysis, EarlyView.
Abstract Introduction This study aims to investigate patient factors affecting the rate of plasma volume target attained in hypertriglyceridemic pancreatitis (HTG‐AP) patients undergoing double filtration plasmapheresis (DFPP). Methods A retrospective analysis of 82 HTG‐AP‐interpreted patients from January 2019 to April 2024 compared target plasma ...
Hui Zhang, Chenqiang Zhu, Yunlong Wu
wiley   +1 more source

Dose Optimization of Teicoplanin for Critically Ill Patients With Renal Dysfunction and Continuous Renal Replacement Therapy: Experience From a Prospective Interventional Study

Frontiers in Pharmacology, 2022
Background: Due to the lack of updated information on teicoplanin (TEI) for continuous renal replacement therapy (CRRT), no exact dosage regimen has been recommended.
Lu Shi, Zhiwei Zhuang, Lufen Duan, Chenqi Zhu, Hongzhi Xue, Xiao Wang, Xiaowen Xu, Yunlong Yuan, Ling Shi, Jiahui Li, Jiantong Sun, Xin Liu, Qin Zhou, Jian Lu, Lian Tang   +14 more
doaj   +1 more source

Paediatric Index of Mortality 3 in Sweden: Validation and Recalibration to Improve Mortality Prediction in Paediatric Intensive Care

Acta Paediatrica, EarlyView.
ABSTRACT Aim In Sweden, critically ill children are admitted to one of four dedicated paediatric intensive care units (PICUs) or general intensive care units (ICUs), reflecting a partly centralised system. The Paediatric Index of Mortality 3 (PIM3) is a widely used risk stratification tool for predicting mortality in critically ill children. This study
Lars Engerström, Shanay Daham, Staffan Eksborg, Tova Hannegård Hamrin, Jonas Berner   +4 more
wiley   +1 more source

Clinical effect and safety of continuous renal replacement therapy in the treatment of neonatal sepsis-related acute kidney injury

BMC Nephrology, 2020
Background Sepsis is the leading cause of acute kidney injury (AKI) in the neonatal intensive care unit (NICU). The aim of the study is to explore the efficacy and security of continuous renal replacement therapy (CRRT) in the treatment of neonatal ...
Cheng Cai, Gang Qiu, Wenchao Hong, Yunlin Shen, Xiaohui Gong   +4 more
doaj   +1 more source

Effects of High‐Fidelity Simulation Training on Learning Outcomes and Satisfaction for Practising Registered Nurses: A Systematic Review and Meta‐Analysis

Journal of Clinical Nursing, EarlyView.
ABSTRACT Background Ample evidence has shown the benefit of high‐fidelity simulation (HFS) in promoting learning in pre‐licensure nursing students, but the evidence for practising registered nurses has not been synthesised. Objective To evaluate the effects of HFS training on learning outcomes and satisfaction in practising registered nurses.
Jie Zhou, Guowen Zhang, Peige Song, Sok Ying Liaw, Tzu Tsun Luk   +4 more
wiley   +1 more source

Epidemiology of continuous renal replacement therapy in Korea: Results from the National Health Insurance Service claims database from 2005 to 2016

Kidney Research and Clinical Practice, 2018
Background : Continuous renal replacement therapy (CRRT) is an important treatment modality for severe acute kidney injury. As such, the epidemiology of CRRT in Korea needs further investigation.
Sehoon Park, Soojin Lee, Hyung Ah Jo, Kyungdo Han, Yaerim Kim, Jung Nam An, Kwon Wook Joo, Chun Soo Lim, Yon Su Kim, Hyeongsu Kim, Dong Ki Kim   +10 more
doaj   +1 more source

Clinical Evaluation of Continuous Renal Replacement Therapy in Combination with Ultrasound-Guided Percutaneous Transhepatic Gallbladder Drainage for Acute Severe Biliary Pancreatitis: a Retrospective Study

Kidney & Blood Pressure Research, 2017
Background/Aims: This study aimed to report the clinical efficacy of continuous renal replacement therapy (CRRT) in combination with ultrasound-guided percutaneous transhepatic gallbladder drainage (PTGD) (CRRT+PTGD) in the treatment of acute severe ...
Qingyun Zhu, Xinting Pan, Yongxian Cao, Hongqiao Wang, Ning Yu, Fuguo Liu, Shigang Yang, Yunlong Wang, Yunbo Sun, Zhengbin Wang   +9 more
doaj   +1 more source

Comparison of the cytokine adsorption ability in continuous renal replacement therapy using polyethyleneimine-coated polyacrylonitrile (AN69ST) or polymethylmethacrylate (PMMA) hemofilters: a pilot single-center open-label randomized control trial

European Journal of Medical Research, 2023
Background Sepsis occurs as a result of dysregulated host response to infection. However, cytokine adsorption therapy may restore the balance of proinflammatory and anti-inflammatory mediator responses in patients with sepsis.
Yoshihiko Nakamura, Hiroki Hatomoto, Shintaro Yamasaki, Kazuya Yamauchi, Fumiaki Kiyomi, Kota Hoshino, Yasumasa Kawano, Takafumi Nakano, Takehiro Hasegawa, Hiroyasu Ishikura   +9 more
doaj   +1 more source

Neonatal Acute Kidney Injury—An Australian and New Zealand Perspective

Journal of Paediatrics and Child Health, EarlyView.
ABSTRACT Acute kidney injury (AKI) is increasingly recognized as a critical and underdiagnosed condition among neonates, with significant short and long‐term implications for survival, kidney function, and long‐term cardiovascular health. Neonatal physiology, including ongoing nephrogenesis, immature renal haemodynamics, and limited glomerular ...
Saumil Desai, Thomas Forbes, Simon A. Carter, Alison L. Kent, Chanel Prestidge, David T. Selewski, Eveline Staub, Anke Raaijmakers   +7 more
wiley   +1 more source