Results 61 to 70 of about 12,656 (183)

Population Pharmacokinetics of Ticagrelor during Veno‐Arterial ECMO in Acute Coronary Syndrome: Model‐Informed Dosing Simulations

Clinical Pharmacology &Therapeutics, Volume 120, Issue 1, Page 193-202, July 2026.
Although patients with acute coronary syndrome supported by veno‐arterial extracorporeal membrane oxygenation (VA‐ECMO) have a high risk of thrombosis and bleeding, antiplatelet pharmacology in this setting is not well defined. This prospective observational study investigated the population pharmacokinetics of ticagrelor and its active metabolite AR ...
Soyoung Kang, Kyoung Lok Min, Seungwon Yang, Jongsung Hahn, Dasohm Kim, Byung Hak Jin, Soon Uk Chae, Soo Kyung Bae, Jin Wi, Min Jung Chang   +9 more
wiley   +1 more source

Polymyxin B Intravenous Administration Strategy Guided by Minimum Inhibitory Concentration in Critically Ill Patients With Pulmonary Infection: Insights From PBPK Modeling

CPT: Pharmacometrics &Systems Pharmacology, Volume 15, Issue 7, July 2026.
PBPK/PD modeling and clinical retrospective validation of intravenous polymyxin B in critically ill patients with pulmonary infection. ABSTRACT Intravenous polymyxin B (PMB) is widely used for treating drug‐resistant gram‐negative pneumonia, though its efficacy in pulmonary infections is considered limited.
Shengnan Zhang, Nan Yang, Ruwei Yang, Yuanfang Qin, Tingting Wu, Cuifang Wu, Yueliang Xie, Jingjing Liu, Chun Liu, Qi Pei   +9 more
wiley   +1 more source

Clarifications on Continuous Renal Replacement Therapy and Hemodynamics

Chinese Medical Journal, 2017
Objective: Continuous renal replacement therapy (CRRT) is a continuous process of bedside blood purification which is widely used in the treatment of acute kidney injury (AKI) and for fluid management.
Xiao-Ting Wang, Cui Wang, Hong-Min Zhang, Da-Wei Liu   +3 more
doaj   +1 more source

Validation of prediction model for successful discontinuation of continuous renal replacement therapy: a multicenter cohort study [PDF]

Kidney Research and Clinical Practice
Background Continuous renal replacement therapy (CRRT) has become the standard modality of renal replacement therapy (RRT) in critically ill patients. However, consensus is lacking regarding the criteria for discontinuing CRRT.
Junseok Jeon, Eun Jeong Ko, Hyejeong Park, Song In Baeg, Hyung Duk Kim, Ji-Won Min, Eun Sil Koh, Kyungho Lee, Danbee Kang, Juhee Cho, Jung Eun Lee, Wooseong Huh, Byung Ha Chung, Hye Ryoun Jang   +13 more
doaj   +1 more source

Extracorporeal Cytokine Hemadsorption for the Treatment of Severe Steroid Refractory Cytokine Release Syndrome Secondary to T‐Cell Immunotherapy for B‐Cell Malignancies: A Case Series

Hematological Oncology, Volume 44, Issue 4, July 2026.
Gianluca Cavallaro, Silvia Ferrari, Anna Pollastri, Elena Di Credico, Cristian Meli, Monica Rondi, Alessandro Putelli, Federico Lussana, Anna Grassi, Alessandro Rambaldi, Tino Martino Valetti, Ivano Riva, Giuseppe Gritti   +12 more
wiley   +1 more source

Knowledge, attitude, practice, needs, and implementation status of intensive care unit staff toward continuous renal replacement therapy: a survey of 66 hospitals in central and South China

BMC Nursing
Background Continuous renal replacement therapy (CRRT) is a commonly utilized form of renal replacement therapy (RRT) in the intensive care unit (ICU).
Xiaoyan Yu, Lin Ouyang, Jinxiu Li, Ying Peng, Dingming Zhong, Huan Yang, Yanyan Zhou   +6 more
doaj   +1 more source

Association of platelet trajectory patterns with in-hospital mortality in critically ill adults with acute kidney injury receiving continuous renal replacement therapy

BMC Nephrology
Background Thrombocytopenia commonly occurs in critically ill patients with acute kidney injury (AKI) receiving continuous renal replacement therapy (CRRT) and is associated with poor outcomes.
Tomonori Takeuchi, Udeme E. Ekrikpo, Joshua W. Lambert, Nathan J. Clay, Diego Sanchez Hernandez, Lan N. Bui, Chloe G. Braun, Stefania Renzi, Kianoush B. Kashani, Ashita J. Tolwani, Javier A. Neyra   +10 more
doaj   +1 more source

Clinical characteristics and prognosis of patients with COVID-19 on mechanical ventilation undergoing continuous renal replacement therapy.

PLoS ONE
BackgroundThe coronavirus disease (COVID-19) pandemic has significantly strained global healthcare, particularly in the management of patients requiring mechanical ventilation (MV) and continuous renal replacement therapy (CRRT).
Dae-Eun Choi, Duk Ki Kim, Sunghoon Park, Su Hwan Lee, Onyu Park, Taehwa Kim, Hye Ju Yeo, Jin Ho Jang, Woo Hyun Cho, Song I Lee, Korean Intensive Care Study Group   +10 more
doaj   +1 more source

Effectiveness and feasibility of continuous renal replacement therapy for acute kidney injury in neonates weighing 3 kg or less: a two-centre, retrospective study

BMJ Paediatrics Open
Background Continuous renal replacement therapy (CRRT) is commonly used for the treatment of acute kidney injury (AKI) in critically ill neonates. This study investigated the effectiveness and feasibility of CRRT for AKI in neonates who weigh ≤3 kg ...
Yifan Sun, Dongmei Chen, Weifeng Zhang, Xiaohui Gong, Cheng Cai, Jinglin Xu, Xiaoyun Chu   +6 more
doaj   +1 more source

Variation of High-Sensitivity Troponin T Results in Patients Undergoing Continuous Renal Replacement Therapy

Canadian Journal of Kidney Health and Disease, 2019
Background: Cardiac troponins are the preferred biomarker to diagnose myocardial injury. Complicating the interpretation of serial troponins in patients with end-stage renal disease, it has been shown that the hemodialysis procedure results in a small ...
Vikas Srinivasan Sridhar, Michael Chen, Howard Gerson, Elizabeth MacNamara, Sharon J. Nessim   +4 more
doaj   +1 more source