Results 171 to 180 of about 5,034,761 (298)

Rhoifolin Alleviates Ulcerative Colitis by Targeting NMNAT1 and Activating SIRT1‐FOXO1 Signaling to Enhance ILC3s Effector Function

Advanced Science, EarlyView.
Rhoifolin directly targets NMNAT1, thereby activating nicotinamide salvage pathway and promoting intracellular NAD+ biosynthesis. Elevated NAD+ levels enhance SIRT1 activity, leading to FOXO1 deacetylation and nuclear translocation. Nuclear FOXO1 subsequently binds to the IL‐22 promoter, upregulating IL‐22 transcription and potentiating ILC3 effector ...
Hongqiong Yang, Yishu Zhang, Sijia Feng, Xiaoqing Ma, Jiayi Feng, Junwei Wang, Jialin Gao, An Pan, Dapeng Wu, Kang Ding, Caijuan Zheng, Qi Lv, Lihong Hu   +12 more
wiley   +1 more source

Effects of Water and Nitrogen Regulation on Alfalfa (<i>Medicago sativa</i> L.) Production Performance Through Optimization of Nitrogen Metabolism. [PDF]

Plants (Basel)
Wang M, Fan H, Zhang Y, Yin M, Kang Y, Qi G, Li B, Yang Y.   +7 more
europepmc   +1 more source

Toward Personalized Theranostics: A Modular PET Platform for Antibody‐Based Imaging and Therapy

Advanced Science, EarlyView.
This modular, site‐specific antibody platform enables customizable conjugates for PET imaging and therapy. Interchangeable payloads – including radiometals, cytotoxics, and fluorophores – support adaptable, multimodal applications with limited off‐target effects. In vivo, the DFO/DOTAGA bischelate immunoconjugate provided clear tumor delineation in PET/
Delphine Vivier, Megane Grah Kple, Julen Ariztia, Marion Leroux, Mathieu Moreau, Michael Claron, Maxime Cheveau, Adam Laouafa, Agnieszka Kownacka, Camille Petitot, John Simonet, Alexandre M. M. Dias, Sophie Poty, Charles Truillet, Bertrand Collin, Alexandra Oudot, Franck Denat   +16 more
wiley   +1 more source

Comprehensive screening and evaluation of eight silage maize varieties in eastern Gansu Province

Siliao yanjiu
The experiment was to select high-yielding and high-quality forage corn varieties suitable for the eastern Gansu Province. Eight silage maize varieties were used as materials, and their agronomic traits, yield traits, and nutritional quality were ...
WANG Yong, ZHANG Xudong, BAI Zushi, WANG Xiaojuan, DONG Xiaofeng, DU Yutang, YANG Xuezhen, ZHENG Qiuyue   +7 more
doaj  

Effects of Dietary Metabolizable Energy and Crude Protein on Postprandial Metabolite Dynamics and Lactation Performance in Dairy Goats. [PDF]

Metabolites
Li X, Wang L, Hu Z, Hou Q, Wang Y, Shen Y, Mu Y, Lin X, Wang Z.   +8 more
europepmc   +1 more source

Evaluation of Tropical Grasses for Forage Yield and Crude Protein Content in the Pothwar Plateau of Pakistan

Journal of Biological Sciences, 2001
Maria Ali, Imtiaz A. Qamar, Asghar Ali ., M. Arshad ., Javed Iqbal .   +4 more
openaire   +1 more source

ATL2 Recruits TRAK1 to Promote Mitochondrial Transport at ER–Mitochondria Contact Sites

Advanced Science, EarlyView.
ABSTRACT Mitochondrial transport and distribution are crucial for cellular homeostasis, yet whether and how they are regulated by endoplasmic reticulum (ER)–mitochondria contact sites remains unclear. Here, we demonstrate that the ER protein atlastin‐2 (ATL2) orchestrates mitochondrial transport and distribution by promoting assembly of the transport ...
Yiru Cheng, Peiyuan Chai, Xiayuhe Pei, Yiwen Chen, Xiaoshuai Huang, Bei Liu, Yiqian Wu, Junlin Teng, Pengli Zheng, Jianguo Chen   +9 more
wiley   +1 more source

First international survey of heavy crude and tar sands

, 1983
In March 1983 the UNITAR/UNDP Information Centre for Heavy Crude and Tar Sands, with the approval of its Advisory Board, decided to organize a world-wide survey of government agencies for information on heavy crude and tar sands resources and production.

core  

Interactive effects of nitrogen rates and deficit irrigation on yield, forage quality, and water productivity of silage sorghum under subsurface drip irrigation. [PDF]

Front Plant Sci
Alagöz M, Türk M.
europepmc   +1 more source

TRIM28‐Derived Peptide Exerts Anti‐Tumor Roles by Stabilizing Tumor Suppressive BRD7 Protein in Multiple Cancers

Advanced Science, EarlyView.
An α‐helical peptide, TAB12, designed to mimic the TRIM28 binding interface, competitively disrupts the TRIM28‐BRD7 interaction, thereby blocking ubiquitin‐mediated degradation of the tumor suppressor BRD7. This stabilization unleashes potent anti‐tumor effects across multiple tumor types with a favorable safety profile, offering a feasible strategy ...
Qingqing Wei, Changning Xue, Mengna Li, Jianxia Wei, Lemei Zheng, Shipeng Chen, Yijie Wang, Yumei Duan, Yanwei Luo, Wei Xiong, Ming Zhou   +10 more
wiley   +1 more source