Results 51 to 60 of about 1,166,410 (270)

Small RNA pathways in mammalian oocytes

FEBS Open Bio, EarlyView.
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

OUTCOME OF DOUBLE KISSING (DK) CRUSH VERSUS PROVISIONAL STENTING FOR LEFT MAIN DISTAL BIFURCATION LESIONS

Pakistan Armed Forces Medical Journal, 2021
Objective: To determine whether a planned 2-stent double kissing crush technique is superior to provisional stenting patients presenting with true distal LM bifurcation lesions. Study Design: Cross-sectional comparative study.
Azmat Ullah, Ali Nawaz Khan, Mohsin Saif, Noor Shah, Javeria Kamran, Kumail Abbas Khan, Abdul Hameed Siddiqui, Sajjad Ali   +7 more
doaj   +2 more sources

The value of the revised trauma score and shock index in patients admitted to the emergency department after an earthquake

Emergency Care Journal
During events like earthquakes that exceed hospital capacities, scoring systems are crucial for prioritizing the injured. This study assessed the predictive accuracy of the Revised Trauma Score (RTS), Shock Index (SI), Modified Shock Index (MSI), and Age-
Halil Oktay Usluer, Akif Yarkaç, Ataman Köse, Çağrı Safa Buyurgan, Seyran Bozkurt, Gülhan Temel   +5 more
doaj   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Identification of (20R)‐protopanaxadiol from Panax ginseng as a novel anti‐SARS‐CoV‐2 compound

FEBS Open Bio, EarlyView.
We established a noninfectious BAC‐based SARS‐CoV‐2 replicon that enables antiviral screening under BSL‐2 conditions. Using this platform, we screened 373 food‐derived compounds and identified (20R)‐protopanaxadiol from Panax ginseng as a novel inhibitor of SARS‐CoV‐2 RNA replication, highlighting the value of safe replicon systems for antiviral ...
Midori Takeda, Natsue Maezono, Rina Uchikoshi, Nobuyuki Kato, Masanori Ikeda   +4 more
wiley   +1 more source

Effect of core crush on honeycomb sandwich panels

, 2010
Nomex honeycomb is used as the predominate core material in aerospace standard sandwich structure. To provide aerospace standard composite face sheets it is necessary to cure the sandwich structure in an autoclave at elevated pressure.
Crump, D.A., Griffith, D., Dulieu-Barton, J.M.   +2 more
core   +1 more source

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

FEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain, Elise Buret, Le Hoang Thanh Nguyen, Marion Cocheteux, Nicolas Touya, Mélanie Dhayer, Romain Dubois, Frank Lafont, Sebastien Janel, Patrice Maboudou, Steve Lancel, Philippe Marchetti   +11 more
wiley   +1 more source

Crush Syndrome Cases Following Spontaneous Collapse of Zümrüt Apartment

Turkish Journal of Nephrology, 2019
When Zümrüt apartment in Konya collapsed spontaneously on monday 02.02.2004, 92 of total 121 people in the apartment at the moment of the incident died and 29 wounded people were rescued from the collapsed building.
Lütfullah ALTINTEPE, İbrahim GÜNEY, H. Zeki TONBUL, Süleyman TÜRK, Mehmet MAZI, Ekrem AĞCA, Mehdi YEKSAN   +6 more
doaj  

After an earthquake : management of crush injuries & crush syndrome [PDF]

"Crush injury and crush syndrome may result from structural collapse during an earthquake. Crush injury is defined as compression of extremities or other parts of the body that causes muscle swelling and/or neurological disturbances in the affected areas

core