Results 41 to 50 of about 3,406,124 (331)

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Santa Cruz e a Fazenda Nacional: notas sobre a situação fundiária

open access: yesColeção Estudos Cariocas, 2004
A Região Administrativa de Santa Cruz (XIX RA), está localizada no extremo oeste do Município do Rio de Janeiro e é composta pelos bairros de Paciência, Santa Cruz e Sepetiba.
Antônio Augusto Veríssimo
doaj   +1 more source

Charles Darwin y las glaciaciones más antiguas de Patagonia: los bloques erráticos del alto valle del Río Santa Cruz [PDF]

open access: yes, 2009
Although the depositational environment assigned by Darwin to the large erratic blocks and gravels in the Río Santa Cruz valley has been reinterpreted, his geomorphological and stratigraphic observations are still in force.
Malagnino, Eduardo Cayetano   +1 more
core  

The evolving fresh market berry industry in Santa Cruz and Monterey counties

open access: yes, 2016
The fresh market berry industry in Santa Cruz and Monterey counties has contributed significantly to the agricultural vibrancy of the two counties and the state of California.

semanticscholar   +1 more source

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

open access: yesMolecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero   +8 more
wiley   +1 more source

Sharp Bekolle estimates for the Bergman projection

open access: yes, 2012
We prove sharp estimates for the Bergman projection in weighted Bergman spaces in terms of the Bekolle constant. Our main tools are a dyadic model dominating the operator and an adaptation of a method of Cruz-Uribe, Martell and Perez.Comment: 12 pages, 1
Pott, Sandra, Reguera, Maria Carmen
core   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham   +21 more
wiley   +1 more source

Stephen Dunn and Warren Maley Volunteer Transplantation Services, Expertise in Bolivia [PDF]

open access: yes, 2016
More than 20 years ago, Stephen P. Dunn, MD, FACS, Professor of Pediatric Surgery at Jefferson, encountered a young liver transplant patient who had traveled from his home in Santa Cruz, Bolivia, to St. Christopher’s Hospital for Children.

core   +1 more source

Equations Defining Toric Varieties

open access: yes, 1995
This article will appear in the proceedings of the AMS Summer Institute in Algebraic Geometry at Santa Cruz, July 1995. The topic is toric ideals, by which I mean the defining ideals of subvarieties of affine or projective space which are parametrized by
Sturmfels, Bernd
core   +3 more sources

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

open access: yesMolecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy   +9 more
wiley   +1 more source

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